Successful treatment of massive pulmonary embolism with low-dose tissue plasminogen activator after meniscus surgery

Pulmonary embolism is a life-threatening disease which represents with high mortality and morbidity. Systemic fibrinolysis is the first-line recommended therapy in hemodynamically instable patients with massive pulmonary embolism. Systemic fibrinolytic treatment remains controversial for pulmonary embolism after surgery due to high risk of hemorrhage. Herein, we report a 49-year-old man with massive pulmonary embolism after meniscus surgery, successfully treated with low-dose prolonged infusion of tissue type plasminogen activator.
Source: Blood Coagulation and Fibrinolysis - Category: Hematology Tags: Case Report Source Type: research