Regulation of T cell immunity by cellular metabolism

AbstractT cells are an important adaptive immune response arm that mediates cell-mediated immunity. T cell metabolism plays a central role in T cell activation, proliferation, differentiation, and effector function. Specific metabolic programs are tightly controlled to mediate Tcell immune responses, and alterations in Tcell metabolism may result in many immunological disorders. In this review, we will summarize the main Tcell metabolic pathways and the important factors participating in Tcell metabolic programming during Tcell homeostasis, differentiation, and function.
Source: Frontiers of Medicine - Category: General Medicine Source Type: research