Synthesis, characterization and the role of ionic radii on the mechanistic of solvothermal for polyazine PtIV complexes: reduction PtIV to PtII, DFT, x-ray single crystal and anticancer studies

Publication date: Available online 11 August 2018Source: Beni-Suef University Journal of Basic and Applied SciencesAuthor(s): Waleed H. Al-Assy, Said A.I. Mahmoud, Dalal Z. Husein, Mohsen M. MostafaAbstractPolypyridyl based on triazine and pyrazine rings with Pt4+, including 2,4,6-tris(2-pyridyl)-1,3,5-triazine (TPT, L1) and 2,3,5,6-tetra(2-pyridyl)-1,4-triazine (TPP, L2), was reported. [Pt34+ (TPT)2Cl8]Cl4.2H2O (1) and [Pt4+(TPP)Cl3]Cl.3H2O (2) were synthesized and characterized. Comparative studies of the solvothermal of Pt4+ complexes and the stability studies of triazine and pyrazine moieties were investigated. Pt2+ complex, [PtII(bpca)Cl], resulted from the metal-promoted solvolysis of L1 to bis-(2-pyridylcarbonyl) amide anion (bpca) and 2-picolinamide, gives yellow single crystal, C12H8ClN3O2Pt (3). The effect of ionic radii of the metal ions has a vital role in solvolysis process. The single crystal shows a square-planar around the Pt2+ ion (3). Crystal data of 3: space group; a = 7.5263 (2) b = 14.1846 (4) c = 22.6884 (7) Å, α = β = γ = 90o, V = 2422.16 (12) Å3, Z = 8. The DFT parameters were calculated to confirm the geometry of complexes. Anticancer activity of complexes was measured.

Source: Beni Suef University Journal of Basic and Applied Sciences - August 11, 2018 Category: Science Source Type: research