Precision Approach to PPI Therapy in Gastroesophageal Reflux Disease

Conditions:   Gastroesophageal Reflux;   Laryngopharyngeal Reflux Intervention:   Diagnostic Test: Reza Band® Upper Esophageal Sphincter (UES) Assist Device Sponsor:   University of Colorado, Denver Recruiting
Source: - Category: Research Source Type: clinical trials

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CONCLUSIONS The study demonstrates that aspiration of gastric contents can cause pulmonary fibrosis, and mixed aspiration of pepsin and gastric fluid can accelerate this process. This study provides strong evidence in support of a potential association between human GERD and IPF. PMID: 31419218 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
The objective of this article is to provide a structured and applicable approach to managing ESRD that is up-to-date and evidence based. To achieve this objective, we created an alphabetized mnemonic and synthesized our discussion to address Anemia, Bone health, Cardiovascular issues, vitamin D deficiency, Electrolytes imbalances, Fluid overload, and Gastroesophageal reflux in patients with ESRD.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Feature Article Source Type: research
Authors: Mohammadifard M, Saremi Z, Rastgoo M, Akbari E Abstract There is evidence that infection by H. pylori can have a critical proportion in the development of hepatocyte injury and both noncancerous and malignant liver conditions including non-alcoholic fatty liver disease (NAFLD). This is attributed to several mechanisms, the most important one being the toxic products of the bacterium H. pylori and oxidative injury for hepatocytes which promotes hepatic injury. The present research was aimed at determining the association between H. pylori infection and the prevalence of NAFLD in Birjand, Iran. Two groups we...
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research
Authors: Michel F, Dannesberger R, Stroh T, Fritsche R, Ahrens P Abstract The findings of functional endoscopy (upper esophageal sphincter insufficiency, cardia insufficiency, esophagitis, gastric heterotopia, axial sliding hernia, and visible aerosols) can be traced back to pharyngeal acid exposure by oropharyngeal pH measurement. Significantly increased pharyngeal acid loads are seen in gastric heterotopy and axial sliding hernia. For all measured statistics, the pharyngeal acid load is in the pathological or even very pathological range. The value of functional endoscopy in the context of laryngopharyngeal reflu...
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
AbstractBackgroundHiatal hernia (HH) repair during laparoscopic sleeve gastrectomy (LSG) has been advocated to reduce the incidence of postoperative gastroesophageal reflux disease (GERD) and/or intrathoracic migration (ITM). The necessity of intraoperative repair in asymptomatic patients is still controversial. Previous, mid-term results of a prospective, comparative study evaluating posterior cruroplasty concomitant with LSG (group A 48 patients with simple vs. group B 48 reinforced with bioabsorbable mesh) confirmed the safety and effectiveness of simultaneous procedures. Present aim was to report the 60  months fo...
Source: Journal of Gastrointestinal Surgery - Category: Surgery Source Type: research
Test your medicine knowledge with the  MKSAP challenge, in partnership with the American College of Physicians. A 35-year-old man is evaluated during a follow-up appointment for persistent heartburn with chronic cough. He has a 1-year history of gastroesophageal reflux disease and takes pantoprazole twice daily. He reports no nausea, vomiting, or dysphagia. Upper endoscopy performed 1 year […]Find jobs at  Careers by  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Gastroenterology Source Type: blogs
Publication date: Available online 6 August 2019Source: Materials Chemistry and PhysicsAuthor(s): Kamini Turan, Prabhsharan Kaur, Dinesh Manhas, Jadab Sharma, Gaurav VermaCarbon nanofibers (CNF) are the state of art materials owing to their special morphological features. In the pristine form, they exhibit strong van der Waals interactions which keep them agglomerated. The actual potential of these nanofibers could be realized once these are unbundled. In this work, CNF have been dispersed with Triton X-100 during ultrasonication, and further functionalized using 3:1 mixture of H2SO4 and HNO3 via reflux method. The effects...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
ConclusionsVonoprazan-first strategy increased QALYs and appeared to be cost-effective for GERD patients compared with the esomeprazole- or rabeprazole-first strategies.
Source: Journal of Gastroenterology - Category: Gastroenterology Source Type: research
CONCLUSIONS: Aspiration can occur in the absence of subjective or demonstrable swallowing difficulties and manifest a broad spectrum of clinico-radiologic presentations. PMID: 31398348 [PubMed - as supplied by publisher]
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
Yvonne Jones, 78, from Stourbridge, West Midlands, was the first in UK to have a new procedure for chronic acid reflux. Here, she discusses her experience.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
More News: Acid Reflux | Gastroenterology | Gastroesophageal Reflux Disease | GERD | Research