Implantable cardioverter-defibrillator use in catecholaminergic polymorphic ventricular tachycardia: A systematic review
The implantable cardioverter-defibrillator (ICD) may be associated with a high risk of complications in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT). However, ICDs in this population have not been systematically evaluated.
Publication date: Available online 15 November 2019Source: Canadian Journal of CardiologyAuthor(s): Xiaofei Li, Xiaohan Fan, Shuang Li, Wei Sun, Kalyanam Shivkumar, Shihua Zhao, Minjie Lu, Yan YaoAbstractBACKGROUNDWe aimed to develop a risk score (ESTIMATED) based on late gadolinium enhancement (LGE) cardiac magnetic resonance to predict sudden cardiac death (SCD) in patients with nonischemic dilated cardiomyopathy (NIDCM) and left ventricular ejection fraction ≤35%.METHODS AND RESULTSWe recruited 395 consecutive middle-aged patients with NIDCM and performed 3-years follow-up for SCD events. The score was developed and ...
Publication date: Available online 15 November 2019Source: Revista Española de Cardiología (English Edition)Author(s): Paolo D. Dallaglio, Loreto Oyarzabal Rabanal, Oriol Alegre Canals, Karina Osorio Higa, Nuria Rivas Gandara, Ignasi Anguera
CONCLUSIONS: Hs-CRP levels rise rapidly among patients with AIP. Maximal hs-CRP levels are associated with MCC. A normal hs-CRP level is rare among patients tested> 24 hours of symptom onset. PMID: 31713364 [PubMed - indexed for MEDLINE]
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AbstractBackgroundDexmedetomidine has been shown to have antiarrhythmic effects by exhibiting sympatholytic properties and activating the vagus nerve in preclinical studies. Results from clinical trials of dexmedetomidine on atrial fibrillation (AF) following adult cardiac surgery are controversial.Materials and methodsWe searched EMBASE, PubMed and Cochrane CENTRAL databases for randomized controlled trials (RCTs) comparing the antiarrhythmic effect of dexmedetomidine versus placebo or other anesthetic drugs in adult patients undergoing cardiac surgery. The primary outcome was the incidence of AF. The secondary outcomes w...
ConclusionOur PPCM collective treated with standard therapy for heart failure, dopamine D2 receptor agonists, and anticoagulation displays a high and stable long ‐term recovery rate with low mortality at 5‐year follow‐up. However, long‐term use of cardiovascular medication, persisting orde novo hypertension and arrhythmias were frequent.
PMID: 31725452 [PubMed - as supplied by publisher]
Despite significant progress in understanding catecholaminergic polymorphic ventricular tachycardia (CPVT), there are still multiple uncertainties and gaps in our knowledge. Like the dark side of the moon, we cannot see them directly. Unfortunately, clinicians must make diagnostic and therapeutic decisions without solid evidence. Instead of summarising the current state of science and reiterating the guidelines, we review difficulties in understanding the disease mechanism, diagnosis and therapy.
Review in-depth clinical information, latest medical news, and guidelines about cardiac arrhythmias, including atrial fibrillation, paroxysmal tachycardia, ventricular tachycardia, and ventricular fibrillation. Read about diagnostic tests for arrhythmia and arrhythmia management.
AbstractOne important complication related to takotsubo syndrome (TTS) is adverse rhythm disorders. Our study was conducted to determine the incidence and management of adverse rhythm disorders in TTS and its long-term prognostic impact. We analyzed 906 TTS patients from 9 European centers. Patients were divided into the adverse rhythm disorders group (encompassing ventricular tachycardia, ventricular fibrillation, torsade de pointes, and asystole or complete atrioventricular block) and non-adverse rhythm disorders group. In our study cohort, we identified 67 (7.4%) patients with presence of adverse rhythm disorders. TTS p...