Clozapine-Induced Acute Hyperglycemia Is Accompanied with Elevated Serum Concentrations of Adrenaline and Glucagon in Rats.

In conclusion, a single administration of clozapine increased the serum concentration of glucose in rats, and adrenaline and/or glucagon would be associated with clozapine-induced acute hyperglycemia.
PMID: 30068879 [PubMed - in process]

Source: Biological and Pharmaceutical Bulletin - August 3, 2018 Category: Drugs & Pharmacology Authors: Nagata M, Kimura Y, Ishiwata Y, Takahashi H, Yasuhara M Tags: Biol Pharm Bull Source Type: research