[ASAP] Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1 < italic toggle="yes" > R < /italic > ,3a < italic toggle="yes" > S < /italic > ,5a < italic toggle="yes" > R < /italic > ,5b < italic toggle="yes" > R < /italic > ,7a < italic toggle="yes" > R < /italic > ,11a < italic toggle="yes" > S < /italic > ,11b < italic toggle="yes" > R < /italic > ,13a < italic toggle="yes" > R < /italic > ,13b < italic toggle="yes" > R < /italic > )-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1 < italic toggle="yes" > H < /italic > -cyclopenta[ < italic toggle="yes" > a < /italic > ]chrysen-9-yl)benzoic Acid (GSK3532795, BMS-955176)

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.8b00854

Source: Journal of Medicinal Chemistry - August 1, 2018 Category: Chemistry Authors: Alicia Regueiro-Ren, Jacob J. Swidorski, Zheng Liu, Yan Chen, Ny Sin, Sing-Yuen Sit, Jie Chen, Brian L. Venables, Juliang Zhu, Beata Nowicka-Sans, Tricia Protack, Zeyu Lin, Brian Terry, Himadri Samanta, Sharon Zhang, Zhufang Li, John Easter, Brett R. Beno Source Type: research