A pharmacokinetic and pharmacodynamic comparison of a novel pegylated recombinant consensus interferon‐α variant with Pegasys in healthy subjects

ConclusionsThe tolerance, pharmacokinetic and pharmacodynamic characteristics of PEG‐IFN‐SA supported its administration by subcutaneous injection, at a single dose of 1.5 μg/kg or 2.0 μg/kg per week.

Source: British Journal of Clinical Pharmacology - October 1, 2014 Category: Drugs & Pharmacology Authors: Li Zheng, Ping Mao Li, Ping Zhong Gou, Wang Ying, Xu Nan, Ming Yong Cai, Hua Luo Tags: PK‐PD relationships Source Type: research