"We are Guinea pigs ”: New documentary explores risks of medical devices

"The Bleeding Edge" filmmakers speak with patients suffering apparent complications from cobalt hip replacements and the Essure permanent birth control device
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news

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Authors: Sfarti VC, Bălan G, Chiriac AŞ, Stanciu C, Bălan G, Gafencu-Şavlovschi D, Trifan AV Abstract AIM: The aim of our study was to compare baseline characteristics and clinical data as well as endoscopic retrograde cholangiopancreatography (ERCP) results in patients with and without periampullary diverticulum (PAD). PATIENTS, MATERIALS AND METHODS: A single center retrospective analysis was conducted from June 2016 to June 2017 and the patients that had undergone ERCP were divided into two groups, according to the presence (Group A, 43 patients) or absence (Group B, 55 patients) of PAD. RESULTS: Mea...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Catastrophic, or life threatening, haemorrhage is recognised as the leading cause of preventable death in trauma patients [1] and is also prevalent in medical conditions such as obstetric complications, gastrointestinal bleeding and surgical patients with intra-operative or post-operative complications [2,3]. Patients are at particular risk of deterioration in the pre-hospital environment. Rapid transport for haemorrhage control intervention is essential [4], however this can be delayed by uncontrollable prehospital factors such as distance, scene accessibility or patient being trapped within a vehicle.
Source: Injury - Category: Orthopaedics Authors: Tags: Review Source Type: research
Intracranial haemorrhage (ICH) risk after minor traumatic brain injury (mTBI) in patients on antithrombotic treatment is unclear. We compared ICH rates in mTBI patients on single, double and no antithrombotic therapy. Antithrombotic drugs encompassed vitamin K antagonists (VKAs), direct oral anticoagulants (DOACs) and antiplatelets. Secondary aim was to identify potential predictors of ICH.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Full Length Article Source Type: research
Factor IX (FIX) is a vitamin K dependent plasma glycoprotein important for blood coagulation as evidenced by significant bleeding diathesis observed in patients with severe hemophilia B – inborn lack of FIX plasma activity. The gene encoding FIX (F9) is located on the X chromosome (q27.1), contains eight exons and spans 34 kb of genomic DNA. Apart from numerous mutations across the F9 resulting in hemophilia B there are two peculiar genetic alterations localized in the F9 prope ptide that may lead to significant FIX deficiency but only in patients who receive vitamin K antagonists (VKAs).
Source: Thrombosis Research - Category: Hematology Authors: Tags: Letter to the Editors-in-Chief Source Type: research
Abstract Objective: We aimed to analyze whether patent foramen ovale (PFO) closure reduces the risk of stroke, assessing also some safety outcomes after the publication of a new trial. Introduction: The clinical benefit of closing a PFO has been an open question, so it is necessary to review the current state of published medical data in regards to this subject. Methods: MEDLINE, EMBASE, CENTRAL/CCTR, SciELO, LILACS, Google Scholar and reference lists of relevant articles were used to search for randomized controlled trials (RCTs) that reported any of the following outcomes: stroke, death, major bleeding or atrial fibrilla...
Source: Revista Brasileira de Cirurgia Cardiovascular - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionHSCT could be an alternative and curative therapeutic option for selectedSTAT1 GOF mutant patients with progressive life-threatening disease unresponsive to conventional therapy. Morbidity and mortality-causing complications included secondary graft failure, infections, and bleeding.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
Conclusions: Laparoscopic pyeloplasty and concomitant flexible renoscopy through lowermost trocar with basket extraction is a simple, attractive alternative for the simultaneous treatment of ureteropelvic junction obstruction presenting with coexisting nephrolithiasis. This method is useful and feasible, with minimal invasiveness and an early post-operative recovery.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Resumo A terapia padr ão com varfarina para a trombose venosa profunda (TVP) tem uma série de limitações já estabelecidas. Essa revisão de revisões sistemáticas elenca os principais resultados de eficácia e segurança dos anticoagulantes orais diretos (DOACs), inibidores da trombina e do fator X ativado (Xa), em pacientes com TVP. A pesquisa foi realizada nas bases PubMed e Cochrane Database of Systematic Reviews. Foram recuperados 23 estudos, e uma revisão sistemática foi considerada elegível. Essa revisão atingiu escore m&aac...
Source: Jornal Vascular Brasileiro - Category: Surgery Source Type: research
We describe the case of a 14-year-old female patient who had been tracheostomized at the age of eight because of head trauma. She later developed subglottic stenosis requiring dilation sessions for six years. During the fifth year of these sessions, she presented repetitive hemoptysis, initially treated by surgery to implant an expanded polytetrafluoroethylene graft. One year later, she had an intense hemorrhage, which was controlled using endovascular techniques followed by definitive surgery, performed electively. The patient was followed up for six months, without complications.
Source: Jornal Vascular Brasileiro - Category: Surgery Source Type: research
We present a case of pseudoaneurysm of the right inferior gluteal artery after a bicycle fall, presenting with a large hematoma in the gluteal region, observed during clinical examination, and significantly reduced hemoglobin. CT angiography revealed a large hematoma, with contrast extravasation and pseudoaneurysm formation. Angiography revealed that the origin of the lesion was in the right inferior gluteal artery. This artery was embolized with coils. After the procedure, the patient was referred to an intensive care unit, from where he was later transferred to a different hospital, with bleeding controlled. Endovascular...
Source: Jornal Vascular Brasileiro - Category: Surgery Source Type: research
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