Monitoring cardiac sarcoidosis: The next frontier

Cardiac sarcoidosis is a potentially life-threatening form of the disease. Although most sarcoidosis-related deaths result from lung involvement, most of these deaths occur after years of the slow development of lung fibrosis from granulomatous inflammation [1,2]. Contrary to pulmonary sarcoidosis, cardiac sarcoidosis may cause life-threatening events and severe organ dysfunction relatively quickly because of myocardial granulomas deposited in unfortunate locations. Furthermore, myocardial sarcoid granulomas tend to progress relatively quickly to scar [3] that does not respond to anti-granulomatous therapy and is permanent.
Source: Respiratory Medicine - Category: Respiratory Medicine Authors: Tags: Editorial Source Type: research