Medical News Today: What to know about end-stage kidney disease

End-stage kidney disease is the last stage of chronic kidney disease when the kidneys stop functioning properly. Without sufficient kidney function, waste products begin to build up in a person's blood, causing a variety of symptoms. In this article, learn about the causes and treatment of end-stage kidney disease.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

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Publication date: Available online 21 May 2019Source: American Journal of Preventive MedicineAuthor(s): Amanda E. Paluch, Lindsay R. Pool, Tamara Isakova, Cora E. Lewis, Rupal Mehta, Pamela J. Schreiner, Stephen Sidney, Myles Wolf, Mercedes R. CarnethonIntroductionNon-white minorities are at higher risk for chronic kidney disease than non-Hispanic whites. Better cardiorespiratory fitness is associated with slower declines in estimated glomerular filtration rate and a lower incidence of chronic kidney disease. Little is known regarding associations of fitness with racial disparities in chronic kidney disease.MethodsA prospe...
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 30 April 2019Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Camilla Pillay, Katherine ClarkAbstractTwenty-three percent of women with known chronic kidney disease (CKD) have been reported to demonstrate the first decline in kidney function between giving birth and six-weeks postpartum. As such, these women warrant close monitoring during the postpartum period irrespective of their pregnancy journey. Substantial haemodynamic variability during pregnancy and postpartum renders estimated glomerular filtration rate inaccurate, and poorly defined normal rang...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Conclusion: There was dose-related increase in Hb across all doses compared to placebo in mITT and per-protocol populations. Desidustat also increased pharmacokinetic parameters Cmax and AUC in dose-related manner. There was no significant change in vital signs, electrocardiographic parameters, or safety laboratory values. Clinical Trial Registration Number CTRI/2017/05/008534 (registered on May 11, 2017).Am J Nephrol 2019;49:470 –478
Source: American Journal of Nephrology - Category: Neurology Source Type: research
Publication date: Available online 20 May 2019Source: Pharmacological ResearchAuthor(s): C. Michael White, Vinay Pasupuleti, Yuani M. Roman, Yangzhou Li, Adrian V. HernandezAbstractTurmeric extract or active component curcumin may have anti-inflammatory effects in people with chronic inflammatory diseases. The effect of turmeric or curcumin on a wide range of inflammatory markers has not been evaluated in a systematic review. We performed a systematic review of randomized controlled trials (RCTs) evaluating the effects of oral turmeric or curcumin on inflammatory markers (CRP, hsCRP, IL-1, IL-6, TNF) in patients with a wid...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Conclusion: Overall, the non-iron containing VMP35 can induce improvements in blood properties and potential benefits for subjects even with compromised digestive systems. No adverse events were reported. Further research studies are in progress to explore the mechanistic insight. PMID: 31105509 [PubMed]
Source: Food and Nutrition Research - Category: Nutrition Authors: Tags: Food Nutr Res Source Type: research
Authors: Fabrizi F, Donato FM, Messa P Abstract INTRODUCTION AND AIM: The role of hepatitis C virus infection as a risk factor for the development and progression of chronic kidney disease in the general population remains unclear. MATERIAL AND METHODS: A systematic review of the published medical literature was performed to assess whether positive anti-HCV serologic status is associated with higher frequency of chronic kidney disease in the adult general population. We used a random-effects model to generate a summary estimate of the relative risk of chronic kidney disease (defined by lowered glomerular filtra...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
In the above-stated article, on page 727 at the end of the first paragraph, the sentence “Serum hepcidin levels increase in response to iron overload and decrease in response to inflammation.” should be “Serum hepcidin levels increase in response to iron overload and inflammation.”
Source: Kidney International - Category: Urology & Nephrology Tags: Corrigendum Source Type: research
The Dietary Approaches to Stop Hypertension (DASH) diet lowers blood pressure and cardiovascular disease risk. In this issue, Banerjee et  al. report that the DASH diet is associated with lower risk of end-stage kidney disease in individuals with stage 3 chronic kidney disease and hypertension. This association was particulary strong among those with diabetes. The DASH diet may have an important role in preventing end-stage kidney di sease in select individuals with chronic kidney disease.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Commentary Source Type: research
Conclusion: Image registration applied to dynamic time series correlated with structural renal changes and should be further explored as a tool for invasive measurements of arteriosclerosis. Significance: Under the assumption that the proposed framework can be further developed in terms of sensitivity and specificity, it can provide clinicians with a non-invasive tool of high spatial coverage available for characterization of arteriosclerosis and potentially other pathological changes observed in chronic kidney disease.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Acute kidney injury (AKI) is a recognized complication of pediatric severe malaria, but its long-term consequences are unknown.
Source: BMC Medicine - Category: Internal Medicine Authors: Tags: Research article Source Type: research
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