Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure d(-)-tartaric acid.

Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure d(-)-tartaric acid.
Chem Commun (Camb). 2018 Jul 13;:
Authors: Dong S, Liu X, Cui GZ, Cui Q, Wang X, Feng Y
Abstract
Crystal structure determination and mutagenesis analysis of a cis-epoxysuccinate hydrolase which produces enantiomerically pure d(-)-tartaric acids revealed a zinc ion and essential residues in the stereoselective mechanism for the catalytic reaction of the small mirror symmetric substrate.
PMID: 30003205 [PubMed - as supplied by publisher]

Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Dong S, Liu X, Cui GZ, Cui Q, Wang X, Feng Y Tags: Chem Commun (Camb) Source Type: research