Reduction of peripheral natural killer cells in patients with SAPHO syndrome.

CONCLUSIONS: Our data suggested that the immune inflammation in SAPHO patients may be related to the depletion of NK cells and the imbalance of Th17 and Treg cells. A reduction of peripheral NK cells may exacerbate the disease progression by not being inhibited Th17 cells.
PMID: 29998837 [PubMed - as supplied by publisher]

Source: Clinical and Experimental Rheumatology - July 14, 2018 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research