High-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds

High-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffoldsHigh-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds, Published online: 10 July 2018; doi:10.1038/s41401-018-0057-zHigh-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds

Source: Acta Pharmacologica Sinica - July 10, 2018 Category: Drugs & Pharmacology Authors: Jia Wang Grace Qun Gong Yan Zhou Woo-Jeong Lee Christina Maree Buchanan William Alexander Denny Gordon William Rewcastle Jackie Diane Kendall James Michael Jeremy Dickson Jack Urquhart Flanagan Peter Robin Shepherd De-Hua Yang Ming-Wei Wang Source Type: research