Molecular Markers and Prognosis of Myelofibrosis in the Genomic Era: A Meta-analysis

In conclusion, mutations in IDH, SRSF2, and ASXL1 had worse prognosis in OS with HRs around 2. JAK2 and SRSF2 mutation were not associated with increased leukemia transformation. The adverse effect of triple-negative, which was often compared with CALR mutation, needs to be explored.

Source: Clinical Lymphoma Myeloma and Leukemia - July 5, 2018 Category: Cancer & Oncology Source Type: research