The Respiratory Infections Team a novel paradigm in the management of community-acquired pneumonia

This shared learning outlines how a Respiratory Infections Team was developed at Royal Derby Hospital, comprising 3 specialist nurses supported by a respiratory consultant and antimicrobial pharmacist. Its aims were to review patients admitted to hospital and to improve concordance with NICE pneumonia guidelines.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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We describe the case of a 75-year-old patient with late-onset schizophrenia who used clozapine. During a hospital admission due to pneumonia, she developed a form of acute dystonia consisting of a rotational torticollis, which disappeared rapidly after treatment with biperiden. Blood examination showed an increase of the clozapine level, probably due to the infection. This case report shows that acute dystonia, although very rare, can occur during treatment with clozapine; therefore awareness is needed of the circumstances that can alter clozapine levels. PMID: 30536298 [PubMed - in process]
Source: Tijdschrift voor Psychiatrie - Category: Psychiatry Authors: Tags: Tijdschr Psychiatr Source Type: research
Condition:   Community-acquired Pneumonia Intervention:   Dietary Supplement: Protein and vitamin supplementation Sponsor:   Birgitte Lindegaard Madsen Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Benton AH, Marquart ME Abstract Streptococcus pneumoniae is a gram-positive, facultatively anaerobic pathogen that can cause severe infections such as pneumonia, meningitis, septicemia, and middle ear infections. It is also one of the top pathogens contributing to bacterial keratitis and conjunctivitis. Though two pneumococcal vaccines exist for the prevention of nonocular diseases, they do little to fully prevent ocular infections. This pathogen has several virulence factors that wreak havoc on the conjunctiva, cornea, and intraocular system. Polysaccharide capsule aids in the evasion of host complement s...
Source: Interdisciplinary Perspectives on Infectious Diseases - Category: Infectious Diseases Tags: Interdiscip Perspect Infect Dis Source Type: research
Authors: Passouant O, Hentzien M, Viguier M, Vernet-Garnier V, Bani-Sadr F, Cousson J PMID: 30528272 [PubMed - as supplied by publisher]
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Medmastery video helps identify the various radiological presentations of pneumonia such as lobar, interstitial , bronchopneumonia and special considerations in immunocompromised patients The post CXR essentials: The many faces of pneumonia appeared first on Life in the Fast Lane.
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Medmastery Respiratory CXR Pneumonia Source Type: blogs
Authors: Ding HG, Zhou HF, Diao MY, Xu Y, Pan QM, Shen XH Abstract OBJECTIVE: Histidine-Rich Glycoprotein (HRG) has been reported to be associated with idiopathic pulmonary fibrosis, cancer, and sepsis as a novel biomarker. However, there is limited evidence regarding its value in diagnosing or prognosis evaluating of ventilator-associated pneumonia (VAP). PATIENTS AND METHODS: A total of 186 patients intubated in ICU and 65 healthy volunteers were enrolled in this study. Patients were divided into VAP group (n = 116), non-VAP group (n = 70) and control group (n = 65). The HRG, C reactive protein (CRP) and proc...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Eosinophilic pneumonia (EP) is a rare and severe disease that belongs to the group of pulmonary eosinophilias (PE). There are two clinical presentations: chronic eosinophilic pneumonia (CEP) and acute eosinophilic pneumonia (AEP). In 1989, Allen et al. described the first case of AEP. 1 Many causes of AEP have been described, although the idiopathic form is the most common.3 We herein present a case of AEP probably due to piperacillin/tazobactam (P/T).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
ConclusionLiver abscess due toKlebsiella pneumoniae is an emerging infection and most commonly reported from Southeast Asia. In Sri Lanka, further studies are necessary to understand the epidemiology and modes of spread. Furthermore, a high index of suspicion is essential as early detection is the key to successful treatment and prevention of complications.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can result in clear clinical benefits in some patients ("friend") but can be ineffective or even associated with undesired side effects, e.g. pneumonia, in others ("foe"). After critically reviewing the evidence for and against ICS treatment in patients with COPD, we propose that: 1) ICS should not be used as a single, stand-alone therapy in COPD; 2) patients most likely to benefit from the addition of ICS to long-acting bronchodil...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Reviews Source Type: research
We performed a meta-analysis to compare the impact of triple combination therapy with inhaled corticosteroids (ICS), long-acting β2-agonists (LABAs) and long-acting muscarinic receptor antagonists (LAMAs) versus LABA/LAMA combination therapy or single long-acting bronchodilator therapy in chronic obstructive pulmonary disease. The ICS/LABA/LAMA combination reduced the risk of exacerbation (relative risk 0.70, 95% CI 0.53–0.94) and improved trough forced expiratory volume in 1 s (mean difference in mL +37.94, 95% CI 18.83–53.89) versus LABA/LAMA combination therapy. The protective effect of triple comb...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Reviews Source Type: research
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