GSE116572 RNA-seq analysis of transcriptomes of Noc4L deficient and the Nco4L sufficient Treg cells

Contributors : Xueping Zhu ; Xuyu ZhouSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo gain in depth transcriptional information about the Noc4L deficeint an Noc4L sufficient Tregs, we performed RNA-seq analysis to compare the transcriptomes of Noc4L sufficient (CD4+GFP+CD62Lhigh, Het) and Noc4L deficient (CD4+GFP+CD62Lhigh, Het) Tregs activated in vitro with Dynabeads for 48 hours or 72 hours. We found ~25 unique genes with differential expression between the Noc4L deficient and Noc4L sufficient Treg cells when activated for 48 hours in vitro. And ~100 unique genes with differential expression between the Noc4L deficient and Noc4L sufficient Treg cells when activated for 72 hours in vitro in two times experiment.

Source: GEO: Gene Expression Omnibus - July 4, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research