[Target volume concepts in radiotherapy and their implications for imaging].

[Target volume concepts in radiotherapy and their implications for imaging].
Radiologe. 2018 Jun 27;:
Authors: Burnet NG, Noble DJ, Paul A, Whitfield GA, Delorme S
Abstract
CLINICAL ISSUE: Successful radiotherapy requires precise localization of the tumor and requires high-quality imaging for developing a treatment plan.
STANDARD TREATMENT: Irradiation of the tumor region, including a safety margin.
TREATMENT INNOVATIONS: The target volume consists of the gross tumor volume (GTV) containing visible parts of the tumor, the clinical target volume (CTV) covering the GTV plus invisible tumor extensions, and the planning target volume (PTV) to account for uncertainties. The non-GTV parts of the CTV are based on historical patient data. The PTV margins are based on a calculation of possible uncertainties during planning, setup, or treatment. Normal tissue deserves the identical care in contouring, since its tolerance may limit the tumor dose, taking into account the contours of organs at risk. Serial risk organs benefit from defining a planning organ of risk volume (PRV) to better limit the dose delivered to them.
DIAGNOSTIC WORK-UP: The better the imaging, the more reliable the definition of the GTV and treatment success will be. Multiple imaging sequences are desirable to support the delineation of the tumor. They may result in different CTVs that, depending on their tumor burden, may require different doses.
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Source: Der Radiologe - June 27, 2018 Category: Radiology Authors: Burnet NG, Noble DJ, Paul A, Whitfield GA, Delorme S Tags: Radiologe Source Type: research