Genetics significantly influence treatment of menopause night sweats

A study published inMenopause reports that genetic differences may be key to find the right oestrogen dose in the treatment of night sweats.Medpage Today
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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(CNN) — UK scientists have developed an online calculator that could enable doctors to more accurately predict a patient’s chance of developing breast cancer. If rolled out, the new tool could change the way in which the condition is treated. Among other things, details of family history, genetics, weight, alcohol consumption, age at menopause and use of hormone replacement therapy will all be considered by doctors when assessing a woman’s risk of developing breast cancer — the most common form of cancer in the UK. Each of these factors has “a small impact on the likelihood of developing the d...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Breast Cancer CNN Local TV Source Type: news
This study aimed to describe the prevalence of upstaging in women with an initial diagnosis of pure DCIS and identify predictive factors of invasion.
MethodsThis is a cross-sectional study including patients with an initial unilateral DCIS diagnosed through needle core or vacuum-assisted biopsy. All patients were submitted to surgical excision. Clinical, radiological and histological variables were retrospectively collected from our medical records.
ResultsA total of 169 biopsies diagnosed with DCIS were included in this study. 53 patients presented upstaging for invasive carcinoma (31.4%). In the univariate analysis t...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Conclusions: Following menopause, we observed a reduction in the relapse rate, but the disability progression continued at a similar rate, compared to the pre-menopausal period. These observations persisted in the subgroup of patients without changes in DMT or co-morbidities diagnosed during the observation period.Eur Neurol 2018;80:223 –227
Source: European Neurology - Category: Neurology Source Type: research
MONDAY, Jan. 14, 2019 -- Postmenopausal women with persistent vasomotor symptoms (VMS) have an increased incidence of breast cancer, according to a study published online Dec. 28 in Menopause. Rowan T. Chlebowski, M.D., Ph.D., from the City of Hope...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
MONDAY, Jan. 14, 2019 -- The Women's Health Initiative (WHI) recommendations for menopausal hormone therapy (MHT) use issued in 2002 have been widely adopted, according to a study published online Dec. 21 in Menopause. Sybil L. Crawford, Ph.D., from...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
Conclusion: The changes in the ovine vaginal wall during representative moments of her lifespan parallel those observed in women.Gynecol Obstet Invest
Source: Gynecologic and Obstetric Investigation - Category: OBGYN Source Type: research
Purpose of review The absolute risk of pregnancy-associated intracranial haemorrhage (ICH) has been reported to be relatively low and often associated with high risks of life-long disabilities and mortality. The aim of this narrative review was obtaining a better understanding of the current management practices for ICH, unruptured aneurysms and/or arteriovenous malformations during pregnancy, as well as the effects of future pregnancies, and the uses of oral contraceptive or HRT. Recent finding General guidelines for the management of ICH are used for pregnant women but additional expedient and thorough evaluation of...
Source: Current Opinion in Neurology - Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Didier Leys Source Type: research
PMID: 30632685 [PubMed - in process]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: BJOG Source Type: research
ConclusionThese results suggest that exercise-induced weight loss and the type of exercise performed may to be critical factors in the modification of the circulation expression of some sex hormones. Further studies are required to elucidate the most effective exercise dose to restore sex hormones homeostasis as potential obesity-breast cancer nexus in the postmenopausal woman.RésuméObjectifL’objectif de cette étude était de faire le point de la littérature scientifique sur l’influence de l’exercice sur les taux circulants d’hormones sexuelles chez les femmes m&eac...
Source: Science and Sports - Category: Sports Medicine Source Type: research
CONCLUSIONS: Men and women display disparate patterns of bone aging. Systemic disenfranchisement of non-white population groups affected bone health in South Africa, and may continue to do so today. Indicators of poor bone quality are evident in the full study sample, indicating that osteoporosis and fracture risk are not just of concern to the aged white female population. PMID: 30628074 [PubMed - in process]
Source: Health Physics - Category: Physics Authors: Tags: Am J Phys Anthropol Source Type: research
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