Genetics significantly influence treatment of menopause night sweats

A study published inMenopause reports that genetic differences may be key to find the right oestrogen dose in the treatment of night sweats.Medpage Today
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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(Natural News) A recently published Danish study found that red clover (Trifolium pratense), a herbaceous plant, can be used to effectively soothe hot flashes and mood swings brought about by menopause. The fermented extract is a remedy of great efficacy. In addition, the extract prevents osteoporosis or bone loss that is accelerated by menopause, which...
Source: - Category: Consumer Health News Source Type: news
Estradiol vaginal inserts (4 µg and 10 µg) for treating moderate to severe vulvar and vaginal atrophy: a review of phase 3 safety, efficacy and pharmacokinetic data. Curr Med Res Opin. 2018 Sep 21;:1-17 Authors: Constantine GD, Simon JA, Pickar JH, Archer DF, Bernick B, Graham S, Mirkin S Abstract OBJECTIVE: To review safety, efficacy, and pharmacokinetic (PK) data from the phase 3 REJOICE trial, which evaluated a 17ß-estradiol (E2) softgel vaginal insert approved in 2018 for moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy (VVA). METHODS: REJOI...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
CONCLUSIONS: Gonadotropin reset, a new therapeutic protocol with GnRHα, was able to improve the ability of testicular spermatogenesis in the NOA patients through restoring the sensitivity of Sertoli and Leydig cells, which were reflected by elevated inhibin B and ameliorative ZO-1 expression and distribution. TRIAL REGISTRATION: identifier: NCT02544191 . PMID: 30243299 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Authors: Li L, Wang Z Abstract Osteoporosis is the most common bone metabolic disease with a very high morbidity, and women usually got a higher risk of osteoporosis than men. The high incidence rate of osteoporosis in women was mainly caused by (1) women having fewer skeletons and bone mass, (2) pregnancy consuming a large amount of calcium and other nutrients, and most importantly (3) the cease of estrogen secretion by ovaries after menopause. Along with ovarian aging, the follicle pool gradually declines and the oocyte quality reduced, accompanied with decline in serum estrogen. Estrogen deficiency plays an impo...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
Publication date: Available online 19 September 2018Source: Indian Heart JournalAuthor(s): Lingkan Barua, Mithila Faruque, Palash Chandra Banik, Liaquat AliAbstractObjectivesThe role of physical inactivity in relation to cardiovascular disease (CVD) among postmenopausal women is understudied. The main objective of this study was to measure the physical activity levels (PAL) and evaluate its relation to other CVD risk factors among postmenopausal rural women of Bangladesh.MethodsA cross sectional study was conducted among 265 postmenopausal women aged 40-70 years who visited the outpatient department of a primary health car...
Source: Indian Heart Journal - Category: Cardiology Source Type: research
(MedPage Today) -- Drop in risk occurred regardless of menopausal status or hormone replacement therapy
Source: MedPage Today Cardiovascular - Category: Cardiology Source Type: news
Authors: Chishti U, Elorbany S, Akhtar M, Williams J, Heenan S, Barton DPJ PMID: 30230398 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Studies have demonstrated increased breast cancer risk associated with postmenopausal hormone therapy, but does risk vary depending on dose, formulation, and route of delivery of estrogen-alone HT?Menopause
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news
In this study, age-related AMH nomograms of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) were produced and compared. 219 rhesus and 529 cynomolgus monkeys ranging from infancy to adult were included. In total, the mean serum AMH levels in cynomolgus monkeys were higher than that of rhesus monkeys (14.6 ± 5.3 ng/ml vs 9.5 ± 6.0 ng/ml, P
Source: General and Comparative Endocrinology - Category: Endocrinology Authors: Tags: Gen Comp Endocrinol Source Type: research
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