Proposed Preoperative Non-invasive Image-guided Breast Brachytherapy (NIBB) Accelerated Partial Breast Irradiation (APBI) Decreases Breast Treatment Volumes Compared with Postoperative NIBB APBI

Following breast conserving surgery, accelerated partial breast irradiation (APBI) is a convenient alternative that allows for reduced normal tissue irradiation as compared to whole breast RT. Toxicity from APBI is related to dose-volume parameters. Non-invasive image-guided breast brachytherapy (NIBB) APBI is associated with reductions in target volumes and normal tissue dose-volume histogram parameters compared to 3D-APBI. Delivery of 3D-APBI in the preoperative (preop) setting allows for reductions in target volumes and sparing of normal tissue.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research