Improved empirical antibiotic treatment of sepsis after an educational intervention: the ABISS-Edusepsis study

Early appropriate antibiotic treatment is essential in sepsis. We aimed to evaluate the impact of a multifaceted educational intervention to improve antibiotic treatment. We hypothesized that the intervention ...
Source: Critical Care - Category: Intensive Care Authors: Tags: Research Source Type: research

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AbstractSocial exclusion and isolation are worldwide social and health concerns with negative effects becoming exacerbated in deprived communities. There is limited understanding related to the role of community ‐based centres in reducing social exclusion and isolation, so the aim of this research was to explore the role one family centre had in improving social inclusion in a deprived community in Glasgow, Scotland. Interpretative Phenomenological Analysis was utilized to analyse interviews from 10 paren ts to explore their lived experiences of creating and developing social networks through family centre attendance. Fi...
Source: Child and Family Social Work - Category: Child Development Authors: Tags: ORIGINAL ARTICLE Source Type: research
Authors: Ravalli S, Szychlinska MA, Lauretta G, Di Rosa M, Musumeci G Abstract Introduction: Osteoarthritis (OA) is a degenerative disease which primarily affects hyaline cartilage, leading to pain, stiffness and loss of mobility of the entire articulation. Diagnosis is commonly based on symptoms and radiographs, but there is a growing interest in detecting novel biomarkers, in serum, urine and synovial fluid, which can be predictors of disease onset and progression.Areas covered: This review provides an overview of the main biomarkers currently used in OA clinical practice, with a focus on lubricin, a surface glyc...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
Publication date: Available online 22 February 2020Source: Sensors and Actuators A: PhysicalAuthor(s): E.A. Sideris, H.C. de LangeAbstractThere has been a substantial amount of research on liquid pumps operated by solid-state electroactive smart material actuators since the first such pump was developed in 1975, providing exciting opportunities for numerous fields. Aiming to motivate researchers to further develop this sector, a taxonomy of representative examples of smart material macro- and micro- diaphragm and linear peristaltic pumps was developed, categorizing them according to pump size and/or amount of fluid hand...
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research
Publication date: Available online 22 February 2020Source: Sensors and Actuators A: PhysicalAuthor(s): M.R. MohebbifarAbstractThe use of a homemade gas leak detector based on laser photo-acoustic spectroscopy for fast and sensitive trace gas detection is reported. To obtain optimal acoustic resonator dimensions, resonant frequency variations in terms of resonator's length and radius were simulated, and then a gas leak detector based on photo-acoustic theory was designed and fabricated. The system limit of detection to trace NO2, SO2 and SF6 was 92, 270 and 8 ppb respectively. Therefore, this system can be used as a ...
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research
Publication date: Available online 22 February 2020Source: Journal of BiotechnologyAuthor(s): Vinoj Chamilka Liyanaarachchi, Gannoru Kankanamalage Sanuji Hasara Nishshanka, Pemaththu Hewa Viraj Nimarshana, Thilini Udayangani Ariyadasa, Rahula Anura AttalageAbstractArtificial neural network (ANN) models can be trained to simulate the dynamic behavior of biological systems. In the present study, an ANN model was developed upon multilayer perceptron neural network architecture with 23-20-1 configuration to predict the cell concentration of microalga Chlorella vulgaris at a given time. Irradiance level, photoperiod, temperatur...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Authors: Lamy S, Houivet E, Benichou J, Marret S, Thibaut F, Perinatal network of Upper-Normandy Abstract Many pregnant women, in the world, drink caffeine-containing beverages. Maternal caffeine consumption during pregnancy may have adverse effects on foetus but results are conflicting. Our goals were to estimate the prevalence of caffeine use in a cohort of French pregnant women using maternal self-reports and to evaluate the association between caffeine consumption during pregnancy and delivery and newborn characteristics. All pregnant women who gave birth in a large French urban area during a limited period of ...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
Authors: Gaudiano BA, Davis CH, Miller IW, Uebelacker L Abstract A common setting where depression is identified and treated is in primary care, where there is a need for low-intensity and cost-effective interventions to be used as part of a stepped-care model. The current study involved a pilot, parallel-group, randomized controlled trial of a video self-help intervention for primary care patients based on Acceptance and Commitment Therapy (ACT). The intervention, called LifeStories, consisted of storytelling vignettes of patients describing their use of ACT-consistent coping skills for depression. Primary care pa...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
Publication date: Available online 22 February 2020Source: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular BiologyAuthor(s): Jing'an Wang, Dongfang Li, Xin Zhao, Tong Sun, Shengzhen Jin, Hongquan Wang, Tiaoyi Xiao, Yaoguo LiAbstractGrowth hormone (ScGH) and growth hormone receptor (ScGHR) genes from the barbel chub (Squaliobarbus curriculus), in addition to their cDNAs, were cloned. The associations between their mRNA expression levels and growth-related traits were analysed, and the differences in the levels of expression of growth regulation-related genes between the largest and smallest indivi...
Source: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology - Category: Molecular Biology Source Type: research
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00104J, PaperPriyanka Halder, Mahesh D. Pol, Milind M Ahire, Santosh B. Mhaske Lewis base-catalyzed allylic alkylation of Morita-Baylis-Hillman adducts with -SCF3 ketones has been demonstrated. The developed strategy provides efficient access to a series of highly functionalized scaffolds featuring trifluoromethanesufinyl motif on... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Authors: Sreeraj VS, Bose A, Chhabra H, Shivakumar V, Agarwal SM, Narayanaswamy JC, Rao NP, Kesavan M, Varambally S, Venkatasubramanian G Abstract Combining cognitive retraining with transcranial direct current stimulation (tDCS) has been hypothesized to improve cognitive deficits in schizophrenia. The effect of combining a neuropsychological/psychophysiological task with tDCS, called "online-tDCS" for cognitive enhancement in schizophrenia is not rigorously assessed. In this proof-of-concept study, we aimed at evaluating the effect of a single session online-tDCS on working memory(WM) and its transferabi...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
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