Clinical evaluation of functional capacity in treatment resistant schizophrenia patients: Comparison and differences with non-resistant schizophrenia patients

Treatment resistant schizophrenia (TRS) is defined by poor or non-response to conventional antipsychotic agents. Functional capacity is defined as the baseline potential of a patient to function in the community, irrespective of actual achievements gained, and has never been studied in TRS. Here, we screened 182 patients with psychotic symptoms and separated them in TRS (n  = 28) and non-TRS (n = 32) ones, to evaluate whether they exhibited differential extents and predictive clinical variables of functional capacity.

Source: Schizophrenia Research - June 19, 2018 Category: Psychiatry Authors: Felice Iasevoli, Luigi D'Ambrosio, Danilo Notar Francesco, Eugenio Razzino, Elisabetta Filomena Buonaguro, Sara Giordano, Thomas L. Patterson, Andrea de Bartolomeis Source Type: research