High prevalence and low spontaneous eradication rate of Helicobacter pylori infection among schoolchildren aged 7 –12 years
Acta Paediatrica, EarlyView.
Condition: Helicobacter Pylori Infection Interventions: Drug: Nitazoxanide; Drug: Clarithromycin; Drug: Metronidazole; Drug: Proton pump inhibitor Sponsor: Tanta University Recruiting
Background and aim Recent clinical trials have confirmed that Helicobacter pylori infection is positively associated with nonalcoholic fatty liver disease (NAFLD), although some research has shown a negative association. Therefore, to confirm whether H. pylori eradication treatment is feasible for NAFLD patients in our hospital, we aimed to establish the association between H. pylori infection and NAFLD. Methods We enrolled 91 patients with NAFLD diagnosed by abdominal B-mode ultrasonography between January and December 2018. H. pylori infection was confirmed by C13 urea breath test, and liver function, glycometabolis...
Authors: Ouyang Y, Li L, Ling P Abstract Helicobacter pylori causes a Gram-negative bacterial infection that can increase the risk of gastric cancer. Consequently, meticulous prevention of an H. pylori infection is significant for averting gastric cancer in humans. Nobiletin, an important dietary polymethoxylated flavonoid in citrus fruits, possesses multidimensional pharmaceutical properties, including its ability to act as an anticancer, anti-inflammatory, antioxidative, cardiovascularly defensive, neuroprotective, and antimetabolic agent. Our study evaluates the role of nobiletin in inflammation-mediated gastric...
Helicobacter pylori (H. pylori) infection is closely associated with gastric cancer, and eradication of H. pylori is currently expected for the prevention of gastric cancer. However, some cases of advanced gastric cancer have been discovered after H. pylori eradication in clinical practice. The aim of our study was to investigate the clinicopathological features of advanced gastric cancer discovered after H. pylori eradication.
The high prevalence of minimal change lesion (MCL) in non-erosive reflux esophagitis (NERD) patients is commonly recognized by many endoscopists. However, it is difficult to detect MCL with conventional white-light imaging (WLI) endoscopy. Linked color imaging (LCI), a novel image-enhanced endoscopy technologies with strong, unique color enhancement, was used for easy recognition of early gastric cancer and detection of H. pylori infection.
H. pylori(HP) infection remains a major risk factor for hypochlorhydria and precancerous lesions leading to gastric cancer.
It has been shown that conventional white light (WL) endoscopic findings often labeled as Helicobacter pylori (H. pylori)-associated gastritis have a poor correlation with confirmative diagnostic tools such as rapid urease test or urea breath test. Although magnifying endoscopy with narrow-band imaging (NBI) is an effective method to predict H. pylori-infected stomach, it is often time consuming and requiring considerable experience and training. Therefore, we investigated the performance of near focus (NF)-NBI, a novel simplified and modest magnifying endoscopy, for predicting H.
Studies of the gastric microbiota showed that Helicobacter pylori (Hp) was not alone and the interaction of Hp with those microorganisms might play a part in Hp associated diseases and Gastro esophageal reflux disease (GERD). The respective roles of these species in development of different diseases including GERD remains to be determined. Metagenomics study can provide new access to the constitution and diversity of the microbiota as well as the function of microbiota in the pathogenesis of GERD in presence or absence of Hp.
This study aimed to determine risk factors related to the development of IM to guide proper management in Thailand.
Since the number of H.pylori-infected persons decreases rapidly, it is expected that acid-related diseases will continue to increase in Japan. The need for gastric acid secretion suppressors is expected to increase in the future. There are several known gastric findings associated with the use of conventional proton pump inhibitors (PPIs). However, there are no reports of gastric findings associated with the use of potassium competitive acid blocker (P-CAB) a more potent gastric acid secretion suppressor.