From supernatants to cytokines: a personal view on the early history of IL-1, IL-1Ra, TNF and its inhibitor in rheumatology

Long-term cell cultures developed early in the twentieth century allowed identification in their supernatants of biological mediators subsequently defined as migration factors, interferons, lymphokines, monoki...

Source: Arthritis Research and Therapy - May 30, 2018 Category: Rheumatology Authors: Jean-Michel Dayer Tags: Commentary Source Type: research