Rad5, HLTF, and SHPRH: A Fresh View of an Old Story.

Rad5, HLTF, and SHPRH: A Fresh View of an Old Story.
Trends Genet. 2018 May 25;:
Authors: Elserafy M, Abugable AA, Atteya R, El-Khamisy SF
Abstract
Not only have helicase-like transcription factor (HLTF) and SNF2 histone-linker PHD-finger RING-finger helicase (SHPRH) proved to be important players in post-replication repair like their yeast counterpart, Rad5, but they are also involved in multiple biological functions and are associated with several human disorders. We provide here an updated view of their functions, associated diseases, and potential therapeutic approaches.
PMID: 29807746 [PubMed - as supplied by publisher]

Source: Trends in Genetics : TIG - May 25, 2018 Category: Genetics & Stem Cells Authors: Elserafy M, Abugable AA, Atteya R, El-Khamisy SF Tags: Trends Genet Source Type: research