Beyond Cut Points: Accelerometer Metrics that Capture the Physical Activity Profile

Purpose Commonly used physical activity metrics tell us little about the intensity distribution across the activity profile. The purpose of this paper is to introduce a metric, the intensity gradient, which can be used in combination with average acceleration (overall activity level) to fully describe the activity profile. Methods A total of 1669 adolescent girls (sample 1) and 295 adults with type 2 diabetes (sample 2) wore a GENEActiv accelerometer on their nondominant wrist for up to 7 d. Body mass index and percent body fat were assessed in both samples and physical function (grip strength, Short Physical Performance Battery, and sit-to-stand repetitions) in sample 2. Physical activity metrics were as follows: average acceleration (AccelAV); the intensity gradient (IntensityGRAD from the log–log regression line: 25-mg intensity bins [x]/time accumulated in each bin [y]); total moderate-to-vigorous physical activity (MVPA); and bouted MVPA (sample 2 only). Results Correlations between AccelAV and IntensityGRAD (r = 0.39–0.51) were similar to correlations between AccelAV and bouted MVPA (r = 0.48) and substantially lower than between AccelAV and total MVPA (r ≥ 0.93). IntensityGRAD was negatively associated with body fatness in sample 1 (P
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: SPECIAL COMMUNICATIONS: Methodological Advances Source Type: research

Related Links:

Authors: Guarda NS, Bollick YS, de Carvalho JAM, Premaor MO, Comim FV, Moresco RN Abstract Background: Uric acid presents different roles in an organism. High serum uric acid concentrations may induce inflammatory pathways and promote kidney damage through different mechanisms. Therefore, this study investigated the association among high serum uric acid concentrations, renal tubular damage, and renal inflammation assessed via estimation of urinary kidney injury molecule-1 (KIM-1) and inflammatory cytokines in patients with type 2 diabetes (T2D). Methods: Urinary concentrations of KIM-1, IL-1, IL-6, IL-10, and ...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Publication date: Available online 23 May 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Yousef Moradi, Hamid Reza Baradaran, Shirin Djalalinia, Ahdieh Chinekesh, Mohamad Ebrahim Khamseh, Maryam Dastoorpoor, Amir-Babak Sioofy-Khojine, Lotfollah Saed, Mostafa QorbaniAbstractComplications among patients with type 2 diabetes mellitus (T2DM) have increased dramatically through two past decades. Thus, the aim of this updated systematic review and meta-analysis was to t estimate the pooled prevalence of T2DM complications in Iranian patients. Using Medical Subject Headings terms, Emtree, a...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 23 May 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): María M. Adeva-Andany, Raquel Funcasta-Calderón, Carlos Fernández-Fernández, Eva Ameneiros-Rodríguez, Alberto Domínguez-MonteroAbstractPatients with diabetes experience increased cardiovascular risk that is not fully explained by deficient glycemic control or traditional cardiovascular risk factors such as smoking and hypercholesterolemia. Asymptomatic patients with diabetes show structural and functional vascular damage that includes impaired vasodilatio...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionmiR-29a-3p played a functional role in insulin receptor signaling in the liver of ZDF rats. YPHL decoction attenuated IR in T2DM probably by down-regulating or maintaining the miR-29a-3p level, increasing the expression of IRS1 mRNA and its phosphorylated proteins, and regulating the expression of insulin receptor signaling-related proteins. YPHL may prove to be an alternative treatment for T2DM.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Condition:   Type 2 Diabetes Mellitus Interventions:   Drug: GX-G6;   Drug: Control Sponsor:   Genexine, Inc. Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Condition:   Diabetes Mellitus, Type 2 Intervention:   Drug: Insulin detemir Sponsor:   Novo Nordisk A/S Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Conclusion: Interaction between the communities and stakeholders was limited, as was engagement in T2D prevention and management. This highlights barriers in the collaboration between community, healthcare institutions and other stakeholders which consequently affect the implementation of preventive interventions. Innovative ways to link the community to the healthcare sector and other local government institutions are needed to build the capacity of health systems for T2D prevention in socioeconomically disadvantaged communities. PMID: 31116096 [PubMed - in process]
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
THURSDAY, May 23, 2019 -- It has long been known that lifestyle affects a person's risk of developing type 2 diabetes. Now, researchers report that they have identified rare variants of four genes that may also play a part. For the study, an...
Source: - Daily MedNews - Category: General Medicine Source Type: news
THURSDAY, May 23, 2019 -- Routine urine samples can be used to test for medication adherence in patients with type 2 diabetes, according to a study published in the June issue of Diabetes Care. Prashanth Patel, M.B.B.S., from the University...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
TYPE 2 diabetes is a lifelong condition which means the need to be extra vigilant at all times, and this includes when on holiday. Sunbathing, medication and the food and drink consumed can all cause symptoms to flare up.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
More News: Diabetes | Diabetes Type 2 | Endocrinology | Girls | Science | Sports Medicine