Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?
We describe in this review what we know about the immunological relevance of post-translationally spliced epitopes and why proteases seem to have a second (dark) personality, which is keen to create new peptide bonds.
PMID: 29723668 [PubMed - as supplied by publisher]
Source: Current Opinion in Immunology - Category: Allergy & Immunology Authors: Liepe J, Ovaa H, Mishto M Tags: Curr Opin Immunol Source Type: research
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