Charged Issues: Particle Radiation Therapy

This issue of Seminars in Radiation Oncology revisits the issue of protons and charged particle radiation, one that was addressed in the April 2013 (volume 23, number 2) issue. We refer the reader to that issue, which included many excellent articles focused on proton and charged particle radiation therapy. Since the time of that publication, the number of charged particle facilities in operation has continued to increase, there has been a significant migration to delivery with scanned beams, and multiple, randomized clinical trials to compare outcomes with protons compared to photons have been activated.
Source: Seminars in Radiation Oncology - Category: Cancer & Oncology Authors: Source Type: research

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In this study, it appears that performing iPET is the most convincing method in improving evaluation and i n finding patients with increased risk of relapse. Evidently, patients with negative iPET will not benefit from including RT in the treatment after metabolic complete response (CR), and patients with primary refractory disease are most likely in the group of positive iPET.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
The field of medical AI is buzzing. More and more companies set the purpose to disrupt healthcare with the help of artificial intelligence. Given how fast these companies come and go, it can prove to be hard to stay up-to-date with the most promising ones. Here, I collected the biggest names currently on the market ranging from start-ups to tech giants to keep an eye on in the future. To further help you keep up with what A.I. brings to medicine, The Medical Futurist team made an easy-to-digest e-book about just that. I highly encourage you to read it and would love to hear about your thoughts! Artificial Intelligence has ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence Healthcare Design AI digital health genetics Innovation Personalized medicine pharma GC1 big data drug development healthcare companies medical imaging Source Type: blogs
Authors: Chen CS, Ou YC, Lin H, Wang CJ, Chen HC, Fang FM, Hsu HC, Huang YJ, Wang YM, Huang CC, Chou SY, Cheng JY, Huang EY Abstract To evaluate clinical outcomes and to identify prognostic factors in isolated para-aortic lymph node (PALN) recurrence, we retrospectively reviewed 65 patients who developed PALN recurrence as the first site of tumor progression from a total of 1521 patients who were treated with curative pelvic radiation therapy (RT) for uterine cervical carcinoma between May 1993 and January 2017. Forty-five of the 65 patients received salvage therapy. The median salvage PALN radiation dose was 54 Gy...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
If you feel like you're working harder just to keep up, you're not mistaken....Read more on AuntMinnie.comRelated Reading: IMV: Global radiologists are optimistic despite local challenges IMV: Imaging boosts precision in radiation therapy IMV: Fixed C-arms improve interventional outcomes IMV: PET/CT drives PET scan volume to new heights IMV: DR now makes up 80% of radiography installed base
Source: Headlines - Category: Radiology Source Type: news
Advances in positron emission tomography (PET) imaging with prostate-specific tracers allow more sensitive and specific detection of low-volume recurrences that were previously indiscernible using conventional imaging. Retrospective data in patients presenting with N1M0 prostate cancer support combined-modality therapy with radiation and androgen deprivation therapy, and preliminary data from the Radiation Therapy Oncology Group 0534 randomized trial suggest that salvage pelvic nodal radiation therapy with androgen deprivation therapy is safe and effective for patients with biochemical recurrence after prostatectomy.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
CONCLUSION: The proposed mp-MRI-guided DIL boost using proton radiation therapy is feasible without violating OAR constraints and demonstrates a potential clinical benefit by improving DIL TCP. This retrospective study suggested the use of IMPT-based DIL SIB may represent a strategy to improve tumor control. ADVANCES IN KNOWLEDGE: This study investigated the planning of mp-MRI-guided DIL boost in prostate proton radiation therapy and estimated its clinical impact with respect to TCP and NTCP. PMID: 31904261 [PubMed - as supplied by publisher]
Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
ConclusionsOncology ‐specific triggers offer a promising method for identifying potential patient safety events among patients across cancer care settings.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
ConclusionsManagement of SNAC consists of histological diagnosis, radiological staging, radical surgery, and adjuvant radiation therapy. Neoadjuvant chemotherapy can be indicated in selected cases. The role of biotherapy and immune therapy still needs to be elucidated.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research
Rationale: Liver transplantation (LT) is the preferred surgical option for the treatment of early hepatocellular carcinoma (HCC). In contrast, surgical treatment of progressive HCC metastasized to the spine following LT constitutes a considerable challenge. Here, we report the first case of progressive HCC metastasized to the T12 vertebra after local radiotherapy, treated successfully with en bloc lumpectomy following LT for HCC. Patient concerns: A 40-year-old man who had undergone LT for the treatment of HCC 2 months prior presented to our clinic with symptoms of progressive back pain. Magnetic resonance imagining (...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Abstract Positron emission tomography (PET) with 18F-fluordeoxyglucose (FDG) in combination with computed tomography (CT) is well established for the diagnostic work-up of patients with head and neck cancer. Possible applications include the detection of an occult primary tumor metastatic to cervical nodes, locoregional staging, assessment of treatment response to external beam irradiation (also in combination with chemotherapy), and surveillance for recurrence. The success of high-precision irradiation techniques such as intensity-modulated radiation therapy (IMRT) appears to be improved by delineating the tumor ...
Source: Nuklearmedizin - Category: Radiology Authors: Tags: Laryngorhinootologie Source Type: research
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