Cellular recording devices imprint the history of the cell

Cellular recording devices imprint the history of the cellCellular recording devices imprint the history of the cell, Published online: 01 May 2018; doi:10.1038/s41581-018-0012-8Technologies such as proteomics provide a snapshot of a specific cellular state but are unable to directly record successive signalling events. Two new CRISPR-mediated analogue multi-event recording apparatus (CAMERA) systems enable sequential recording of endogenous and exogenous signalling events by targeted DNA modifications, thereby allowing systematic interrogation of different cellular states.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research