361 Successful treatment of calciphylaxis related to lupus erythematosus in a non-uremic, euparathyroid state: Case report and discussion

Calciphylaxis, an aggressive and difficult to treat vasculopathy, occurs most commonly in association with end-stage renal disease (ESRD). It rarely occurs in patients without end-stage renal disease (ESRD), referred to as non-uremic calciphylaxis (NUC) in such settings. Herein, we present a case of NUC in a patient with a complex rheumatologic history and discuss the pathophysiologic mechanisms driving NUC development. A 60-year-old woman with systemic lupus erythematosus (SLE), myasthenia gravis (MG), and Sjogren syndrome (SS) was transferred to our hospital for evaluation of longstanding and intensely painful lower extremity wounds.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Clinical Research: Epidemiology of Skin Diseases Source Type: research