Preoperative Hyponatremia Is Associated with Reoperation and Prolonged Length of Hospital Stay following Total Knee Arthroplasty

J Knee Surg DOI: 10.1055/s-0038-1641156Hyponatremia is a risk factor for adverse surgical outcomes, but limited information is available on the prognosis of hyponatremic patients who undergo total knee arthroplasty (TKA). The purpose of this investigation was to compare the incidence of major morbidity (MM), 30-day readmission, 30-day reoperation, and length of hospital stay (LOS) between normonatremic and hypontremic TKA patients.The American College of Surgeons National Surgical Quality Improvement Program database was used to identify all primary TKA procedures. Hyponatremia was defined as 145 mEq/L) were excluded. Multivariable logistic regression was used to determine the association between hyponatremia and outcomes after adjusting for demographics and comorbidities. An α level of 0.002 was used and calculated using the Bonferroni correction. Our final analysis included 88,103 patients of which 3,763 were hyponatremic and 84,340 were normonatremic preoperatively. In our multivariable models, hyponatremic patients did not have significantly higher odds of experiencing an MM (odds ratio [OR]: 1.05; 99% confidence interval [CI] 0.93–1.19) or readmission (OR: 1.12; 99% CI: 1–1.24). However, patients with hyponatremia did experience significantly greater odds for reoperation (OR: 1.24; 99% CI: 1.05–1.46) and longer hospital stay (OR: 1.15; 99% CI: 1.09–1.21). We found that hyponatremic patients undergoing TKA had increased odds of reoperation an...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research

Related Links:

Abstract Laryngeal trauma from prolonged endotracheal intubation occurs in patients of all ages. Most changes are superficial and heal quickly. Injuries that are found consistently during intubation include nonspecific changes, edema, granulation tissue, ulceration, and othermiscellaneous injuries. In thispapersignificant, severe, and lasting trauma of the larynx has been classified on thebasis of theknown factors in pathogenesis, observations made atendoscopy, and photographic documentation. This classification has required introduction of new descriptive terminology: "tongues of granulation tissue," &q...
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
PMID: 30012011 [PubMed - in process]
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
PMID: 30012010 [PubMed - in process]
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
PMID: 30012009 [PubMed - in process]
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
The FDA has approved the first protease inhibitor-based single-tablet regimen for the treatment of HIV-1 infection in treatment-naive and certain virologically suppressed adult patients.FDA Approvals
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: HIV/AIDS News Alert Source Type: news
Publication date: August 2018Source: The Lancet Neurology, Volume 17, Issue 8Author(s): Henk-Jan Westeneng, Ammar Al-Chalabi, Orla Hardiman, Thomas PA Debray, Leonard H van den Berg
Source: The Lancet Neurology - Category: Neurology Source Type: research
Publication date: August 2018Source: The Lancet Neurology, Volume 17, Issue 8Author(s): Susana Carmona, Kathleen Zahs, Elizabeth Wu, Kelly Dakin, Jose Bras, Rita GuerreiroSummaryAlzheimer's disease is a genetically complex disorder; rare variants in the triggering receptor expressed on myeloid cells 2 (TREM2) gene have been shown to as much as triple an individual's risk of developing Alzheimer's disease. TREM2 is a transmembrane receptor expressed in cells of the myeloid lineage, and its association with Alzheimer's disease supports the involvement of immune and inflammatory pathways in the cause of the disease, rather th...
Source: The Lancet Neurology - Category: Neurology Source Type: research
Publication date: August 2018Source: The Lancet Neurology, Volume 17, Issue 8Author(s): Farhat Husain, Jerry Vanatta
Source: The Lancet Neurology - Category: Neurology Source Type: research
Publication date: August 2018Source: The Lancet Neurology, Volume 17, Issue 8Author(s):
Source: The Lancet Neurology - Category: Neurology Source Type: research
Publication date: August 2018Source: The Lancet Neurology, Volume 17, Issue 8Author(s): Lee H Schwamm
Source: The Lancet Neurology - Category: Neurology Source Type: research
More News: Databases & Libraries | Hospitals | Study