[Correspondence] Outcome assessment after traumatic brain injury – Authors' reply

We thank Thomas McMillan and colleagues for their thoughtful comments on assessment of outcomes, with many of which we fully agree. As with many outcome assessments in traumatic brain injury (TBI), the Glasgow Outcome Scale (GOS) is open to a wide variety of influences other than brain injury: factors related to acute TBI appear to explain at best 35% of the variance.1 The predictors, moderators, and mediators of outcome after TBI are incompletely understood. There is thus much progress to be made in identifying confounding covariates for the effects of interventions.

Source: Lancet Neurology - March 14, 2018 Category: Neurology Authors: Lindsay Wilson, Nicole von Steinbuechel, David K Menon, Andrew I R Maas Tags: Correspondence Source Type: research