"siRNA traffic lights": Arabino-configured 2'-anchors for fluorescent dyes are key for dual color readout in cell imaging

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB00417J, PaperJeannine Steinmeyer Steinmeyer, Heidi-Kristin Walter, Mathilde Bichelberger, Violetta Schneider, Tomas Kubar, Franziska Ronicke, Bettina Olshausen, Karin Nienhaus, Gerd Ulrich Nienhaus, Ute Schepers, Marcus Elstner, Hans-Achim Wagenknecht Two fluorescent dyes are covalently attached in diagonal interstrand orientation to siRNA undergo an energy transfer and thereby enable a dual color fluorescent readout (red/green) for hybridization. Three different structural... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - March 13, 2018 Category: Molecular Biology Authors: Jeannine Steinmeyer Steinmeyer Source Type: research