Morning Break: Flu Vaccine Hype; Suburban Rabies Scare; Jet Lag Drug Win
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff
Updated Date: Aug 13, 2018 EST
Guangxi is the province most seriously affected by rabies virus (RABV) in China. Those most affected by RABV each year are people in rural areas, where dogs are the main cause of human infection with the virus.
Changsheng Bio-technology Co Ltd, a vaccine maker at the center of a safety scandal in China, began falsifying production records for its rabies vaccine in April 2014, state news agency Xinhua reported on Tuesday.
Publication date: 1 October 2018Source: Preventive Veterinary Medicine, Volume 158Author(s): Fatima Yahiaoui, Moustafa Kardjadj, Younes Laidoudi, Hacène Medkour, Meriem Hind Ben-MahdiAbstractRabies is a neglected zoonotic disease. Several animal species can transmit rabies, but domestic dogs are the main reservoir implicated in rabies transmission to human and other susceptible animals. There is a scarcity of data regarding canine rabies in Algeria. Hence, this report is the first study that attempts to understand the epidemiology of dog rabies through a retrospective national study of rabies cases between 2010 and ...
Rabies kills an estimated 20,000 people in India every year, according to the government's National Rabies Control Programme.
by Mirjam Laager, C éline Mbilo, Enos Abdelaziz Madaye, Abakar Naminou, Monique Léchenne, Aurélie Tschopp, Service Kemdongarti Naïssengar, Timo Smieszek, Jakob Zinsstag, Nakul Chitnis Canine rabies transmission was interrupted in N’Djaména, Chad, following two mass vaccination campaigns. However, after nine months cases resurged with re-establishment of endemic rabies transmission to pre-intervention levels. Previous analyses investigated district level spatial heterogeneity of vaccination coverage, and dog density; and importation, identifying the latter as the primary factor for ra...
Abstract This infographic describes the transmission cycle of rabies virus in domestic dogs and the necessity of a One Health approach, integrating medical and veterinary interventions, to control and eliminate human rabies deaths. Rabies virus (RABV) causes an acute, fatal neurological infection in humans and other mammals, transmitted through the saliva of rabid animals via a bite or scratch. From the site of infection the virus travels along neurons to the central nervous system (CNS), where viral replication leads to symptoms and systemic spread. Once symptomatic, the disease is nearly 100% fatal. However, the...
This study aims to explore this knowledge gap, by providing factors and possible mechanisms that can explain children's involvement in the rabies post-exposure prophylaxis. This study was conducted in Bajawa district, Flores East Nusa Tenggara, Indonesia.
Background: Rabies is a viral neglected disease considered fatal, that affects mammals and with only 12 cases of survival reported in humans. Despite the existence of preventive vaccines, rabies still represents a serious public health problem, with a major impact in vulnerable populations around the world, causing about 55,000 human deaths per year. The membrane glycoprotein of the rabies virus (RVGP), specifically the ectodomain portion, has been intensively studied for the development of recombinant proteins, due to its ability to interact with neutralizing antibodies and induce immune responses.
Background: Rabies is a zoonotic viral disease endemic in many countries, with sporadic epidemics. It is classified as a neglected tropical disease even though more than three billion people live in regions where rabies occurs. The virus is transmitted to humans mainly by rabid dogs, therefore mass vaccination of dogs is the mainstay of successful canine rabies control. The rabies virus glycoprotein (RVGP) is the antigen responsible for the induction of neutralizing antibodies protecting it against the viral infection.