Tumor-targeted Fluorescence May Help Pinpoint Colorectal Cancer During Surgery Tumor-targeted Fluorescence May Help Pinpoint Colorectal Cancer During Surgery
Reuters Health Information
Conclusions: These results affirm that patients with OMCC have extended OS periods and that stereotactic body radiotherapy offers strong local control in these settings. We show that even in the oligometastatic setting those with right-sided primary tumors have worse outcomes relative to those with left-sided or rectal primary tumors. This suggests more aggressive treatment may be needed for those with oligometastatic right-sided colorectal cancer.
This study investigated the addition of celecoxib, a selective COX-2 inhibitor, to the irinotecan, 5-fluorouracil, and leucovorin (IFL) regimen for patients with previously untreated metastatic CRC. Patients and Methods: Forty-seven patients enrolled in this single-arm phase II study received celecoxib at 400 mg orally twice daily in combination with weekly irinotecan (125 mg/m2), 5-fluorouracil (500 mg/m2), and leucovorin (20 mg/m2) for 4 weeks every 6 weeks. The primary endpoint was response rate (RR) as measured by Response Evaluation Criteria in Solid Tumors. The protocol was amended midw...
Authors: Jiang H, Tang E, Xu D, Chen Y, Zhang Y, Tang M, Xiao Y, Zhang Z, Deng X, Li H, Lin M Abstract [This corrects the article DOI: 10.18632/oncotarget.16167.]. PMID: 30450164 [PubMed - in process]
Authors: Gráf L, Barabás L, Madaras B, Garam N, Maláti É, Horváth L, Prohászka Z, Horváth Z, Kocsis J Abstract BACKGROUND: Hsp70 plays important role in the development and progression of cancer. Previously we described the association between serum Hsp70 levels and mortality of colorectal cancer. OBJECTIVE: In this new prospective study we aimed to confirm and extend our previous findings in a larger cohort of patients, based on a longer follow-up period. METHODS: Two hundred and thirty-two patients diagnosed with colorectal cancer were enrolled in the study...
A new clinical trial suggests that taking aspirin and an omega-3 fatty acid can decrease the number of precancerous growths in the colon.
Zhen Zong, Hui Li, Chenghao Yi, Houqun Ying, Zhengming Zhu, He Wang
ConclusionIn this review, we summarize pathways and mechanisms of ferroptosis in HCC and other digestive system neoplasms such as gastric cancer, pancreatic cancer and colorectal cancer and point out the trends of ferroptosis in HCC.
Dante Labs sent me their Full DNA whole genome sequencing package, and I went through a roller-coaster of feelings: I was excited to know every secret of my cells, but I was afraid to get to know my hereditary cancer risks and worried what I might find. As in my case, (scientific) curiosity usually overrides fear, I jumped into the unknown and I’m eager to share my results here. Whole genome sequencing is available to anyone. So what? The human genome is the blueprint for building a person. When the Human Genome Project was completed in 2006, and the DNA double spiral uncovered its secrets for the very first time, sc...
Jing Cong, Hua Zhu, Dong Liu, Tianjun Li, Chuantao Zhang, Jingjuan Zhu, Hongying Lv, Kewei Liu, Chenxing Hao, Zibin Tian, Jianli Zhang, Xiaochun Zhang
Current cancer screening efforts have not sufficiently invested in optimizing...Read more on AuntMinnie.comRelated Reading: ACS lowers colorectal cancer screening age to 45 Cancer deaths continue to fall, but CT lung screening lags ACS: U.S. cancer death rates continue to fall ACS report shows cancer rates still falling Report finds U.S. cancer death rate still dropping