Anti-CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritis-prone Fc γRIIB-deficient mice

Previously we established an arthritis-prone Fc γRIIB-deficient mouse strain (designated KO1). Anti-mouse CD11b mAb (5C6) has been reported to inhibit the recruitment of peripheral CD11b+ myelomonocytic cells from...

Source: Arthritis Research and Therapy - February 8, 2018 Category: Rheumatology Authors: Mareki Ohtsuji, Qingshun Lin, Hideki Okazaki, Kazuko Takahashi, Hirofumi Amano, Hideo Yagita, Hiroyuki Nishimura and Sachiko Hirose Tags: Research article Source Type: research