Medical News Today: Asparagus amino acid helps deadly breast cancer to spread

An amino acid derived from a wide range of foods, including asparagus, helps triple-negative breast cancer to spread in the body, a new study has found.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Breast Cancer Source Type: news

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Background: Second primary malignancies (SPM) in the lung are not common in breast cancer (BC) patients.EGFR-mutant lung cancer (LC) is a separate molecular subset, and the co-existence ofEGFR-mutant LC and BC has not been explored. We hypothesized thatEGFR-mutant LC patients could have higher rates of primary BC than those withEGFR-wild type (WT).Methods: We collected data on clinical and molecular characteristics and outcomes of female patients with LC and a previous or simultaneous history of primary BC treated in our hospital from 2008 to 2014.Results: Data on treatment, follow-up, andEGFR mutation status were availabl...
Source: Oncology Research and Treatment - Category: Cancer & Oncology Source Type: research
However, many report feeling uncomfortable or believing they lack the necessary knowledge
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Internal Medicine, Nursing, Oncology, Radiology, Surgery, Journal, Source Type: news
Publication date: Available online 21 February 2019Source: Journal of the Taiwan Institute of Chemical EngineersAuthor(s): Chih-Hsiang Chang, I-Chi Tsai, Chung-Jen Chiang, Yun-Peng ChaoAbstractThe heterogeneous nature of cancers renders the efficacy of the therapeutic treatment diversified. To address this issue, a theranostic approach was proposed by development of a hybrid peptide for simultaneous diagnosis and therapy of cancer cells. Peptide A was composed of the biotinylation site (BS), the HER2/neu-binding motif, and the dockerin domain (Doc). Peptide B was designed with BS and the cohesin domain (Coh). Individually ...
Source: Journal of the Taiwan Institute of Chemical Engineers - Category: Chemistry Source Type: research
Publication date: Available online 22 February 2019Source: Chinese Chemical LettersAuthor(s): Chao Song, Dan Gao, Tianying Yuan, Yongli Chen, Liping Liu, Xiaowu Chen, Yuyang JiangAbstractCell migration and invasion are critical steps in cancer metastasis, which are the major cause of death in cancer patients. Tumor-associated macrophages (TAMs) and interstitial flow (IF) are two important biochemical and biomechanical cues in tumor microenvironment, play essential roles in tumor progression. However, their combined effects on tumor cell migration and invasion as well as molecular mechanism remains largely unknown. In this ...
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research
Dalton Trans., 2019, Advance Article DOI: 10.1039/C9DT00335E, CommunicationYan Guo, Shuren Zhang, Hao Yuan, Dongfan Song, Suxing Jin, Zijian Guo, Xiaoyong Wang A PtIV prodrug bearing a vascular disrupting agent demonstrates antiangiogenic and antimetastatic potentialities against metastatic triple-negative breast cancer cells. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Publication date: Available online 21 February 2019Source: The Lancet Global HealthAuthor(s): Peter C Rockers, Richard O Laing, Paul G Ashigbie, Monica A Onyango, Carol K Mukiira, Veronika J WirtzSummaryBackgroundNovartis Access is a Novartis programme that offers a portfolio of non-communicable disease medicines at a wholesale price of US$1 per treatment per month in low-income and middle-income countries. We evaluated the effect of Novartis Access in Kenya, the first country to receive the programme.MethodsWe did a cluster-randomised controlled trial in eight counties in Kenya. Counties (clusters) were randomly assigned ...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Authors: Liu J, Liu J, Lu X Abstract Breast cancer (BC) is the most commonly diagnosed cancer and the second leading cause of cancer-associated mortality among females worldwide. As a member of the homeobox (HOX) gene family, HOXA1 is involved in tumor progression and prognosis in several types of human cancer. However, the clinical significance and biological functions of HOXA1 in BC remains unknown. The current study assessed the expression of HOXA1 in BC tissues and cells via western blotting and reverse transcription-quantitative polymerase chain reaction. The association between HOXA1 expression and the clinic...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
In this study, three non-linear indices consist of compression, one-dimensional (1D) and two-dimensional (2D) fractal dimensions are used for the determination of the malignancy or benignity of cancer tumours in breast thermograms. On the other hand, by developing the high-precision infrared cameras as well as new methods of image processing, biomedical thermography images have found a prominent position among the others. Furthermore, cancerous tissue can be affected by the laser. In this study, in order to treat the cancerous lesion identified by breast thermograms, the laser parameters are designed. The basis of controll...
Source: IET Systems Biology - Category: Biology Source Type: research
Biologic age, a DNA-based estimate of a person’s age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health. Biologic age was determined by measuring DNA methylation, a chemical modification to DNA that is part of the normal aging process. The study showed for every five years a woman’s biologic age was older than her chron...
Source: NIEHS - National Institute of Environmental Health Sciences - News - Category: Environmental Health Source Type: research
(NIH/National Institute of Environmental Health Sciences) Biologic age, a DNA-based estimate of a person's age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health. Biologic age was determined by measuring DNA methylation, a chemical modification to DNA that is part of the normal aging process. For every five years a woman's biologic age was older than her chronologic or actual age, she had a 15 percent increased risk of developing breast cancer.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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