Medical News Today: Asparagus amino acid helps deadly breast cancer to spread
An amino acid derived from a wide range of foods, including asparagus, helps triple-negative breast cancer to spread in the body, a new study has found.
Jie Wang, Gejing De, Qiaoxin Yue, Hai Ma, Jintang Cheng, Guangwei Zhu, Maobo Du, Hong Yi, Qinghe Zhao, Yanjun Chen
Hua Xing, Lirong Zhang, Jinshu Ma, Zhen Liu, Changlong Song, Yuxia Liu
(Wiley) In a BJS (British Journal of Surgery) analysis of 18,730 older patients with estrogen receptor-positive breast cancer in the UK, the risk of dying from breast cancer was greater in patients treated with primary endocrine therapy than in those who received surgery.
CONCLUSIONS In conclusion, our results suggest that IQGAP1 plays an important role in the cell proliferation and invasion of human breast cancer cells, thus indicating that IQGAP1 may be a potential therapeutic target for the treatment of human breast cancer. PMID: 29779034 [PubMed - in process]
AbstractBreast cancer metastasizes through the lymphovascular system to the regional lymph nodes in the axilla and to both visceral and non-visceral sites. Renewed interest in the route by which tumor cells gain access to blood and lymphatic capillaries are the subject of research at mechanical, anatomic, pathologic, genetic, epidemiologic and molecular levels. Two papers presented at the 7th International Symposium on Cancer Metastasis in San Francisco showed tumor cells entering the systemic circulation through the sentinel lymph node. This information challenges the current paradigm where clinicians believe that access ...
Publication date: Available online 22 May 2018 Source:Clinical Epidemiology and Global Health Author(s): Sumita Shankar, Manaswitha Boyanagari, Vamsi Krishna Boyanagari, Mehul Shankar, Ravi Shankar Ayyanar
Conclusions/Implications for Practice: The FIS has acceptable reliability, content validity, and construct validity. This scale is appropriate for use in research and clinical practice settings to evaluate the risk–benefit perceptions of pregnancy in patients with breast cancer.
(Natural News) A shocking new report has revealed a sordid truth about yet another one of Big Pharma’s cancer “treatment” concoctions: Lapatinib, used in breast cancer treatment to shrink tumors, actually makes cancer grow faster. There is no shortage of cancer drugs that makes people sicker, instead of healthier, it seems. Lapatanib is typically used...
Conclusions: This SEER analysis demonstrates that a substantial proportion of women with early stage breast cancer are eligible for HFRT, APBI, or ET alone after breast conserving surgery according to consensus guidelines and prospective trial criteria. With incorporation of additional pathologic, dosimetric, and chemotherapy data, quality assurance pathways may use such data to help ensure patients are receiving appropriate risk stratified treatment recommendations.
Objectives: Invasive papillary breast cancer (IPBCA) represents 0.5% of invasive BCA, and is thought to carry a favorable prognosis. This population-based study reports on prognostic factors, treatment, and outcomes of early-stage IPBCA to explore whether there is any evidence to support less aggressive treatment. Materials and Methods: IPBCA cases from 1990 to 2009 of the recent Surveillance, Epidemiology, and End Results were analyzed. Inclusion criteria included patients with stage T1-2, N0 IPBCA. Univariate and multivariate analyses were performed using the variables of treatment, stage, race, hormone receptor sta...