GP practices urged to order new flu vaccine for next winter

GP surgeries in England have been told to order a new adjuvanted trivalent vaccine (aTIV) to ensure the most vulnerable get “gold standard” protection against influenza next winter.
Source: Nursing Times - Category: Nursing Source Type: news

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FRIDAY, Dec. 14, 2018 -- Racial disparities exist among adolescents undergoing influenza vaccination, with lower odds of vaccination among black versus white adolescents, according to a study recently published in Public Health Reports. Noah S....
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Influenza viruses cause contagious respiratory infections, resulting in significant economic burdens to communities. Production of influenza-specific Igs, specifically IgGs, is one of the major protective immune mechanisms against influenza viruses. In humans, N-glycosylation of IgGs plays a critical role in antigen binding and effector functions. The ferret is the most commonly used animal model for studying influenza pathogenesis, virus transmission, and vaccine development, but its IgG structure and functions remain largely undefined. Here we show that ferret IgGs are N-glycosylated and that their N-glycan structures ar...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Glycobiology and Extracellular Matrices Source Type: research
Publication date: Available online 12 December 2018Source: The Lancet Respiratory MedicineAuthor(s): Christopher E Troeger, Brigette F. Blacker, Ibrahim A. Khalil, Stephanie R M Zimsen, Samuel B. Albertson, Degu Abate, Jemal Abdela, Tara Ballav Adhikari, Sargis Aghasi Aghayan, Sutapa Agrawal, Alireza Ahmadi, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, Ayman Al-Eyadhy, Rajaa M Al-Raddadi, Fares Alahdab, Kefyalew Addis Alene, Syed Mohamed Aljunid, Nelson Alvis-GuzmanSummaryBackgroundAlthough the burden of influenza is often discussed in the context of historical pandemics and the threat of future pande...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Optical super-resolution microscopy techniques enable high molecular specificity with high spatial resolution and constitute a set of powerful tools in the investigation of the structure of supramolecular assemblies such as viruses. Here, we report on a new methodology which combines Structured Illumination Microscopy (SIM) with machine learning algorithms to image and classify the structure of large populations of biopharmaceutical viruses with high resolution. The method offers information on virus morphology that can ultimately be linked with functional performance. We demonstrate the approach on viruses produced for on...
Source: eLife - Category: Biomedical Science Tags: Epidemiology and Global Health Microbiology and Infectious Disease Source Type: research
​BY GREGORY TAYLOR, DO; DAWN ZELENKA-JOSHOWITZ, DO; &ANDREW TAECKER, DOA 34-year-old man presented with intermittent fever and body aches for 10 days. He had been visiting family in India, and the symptoms began when he returned home. His fever had been as high as 104°F, and he was experiencing nausea, two episodes of bilious emesis, body aches, nonspecific abdominal pain, and multiple episodes of watery, nonbloody diarrhea.He said he knew of no tuberculosis exposure or ill contacts, and he was current on his routine influenza and hepatitis A vaccines. His temperature was 101.4°F (he had taken acetaminophen t...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Conclusions: The HDV versus SDV comparison yielded less-biased estimates of the all-cause mortality before influenza season compared to those with nonuser comparison groups. Vaccine effectiveness and safety researchers should consider the active comparator design to reduce bias due to differences in underlying health status between vaccinated and unvaccinated individuals.
Source: Medical Care - Category: Health Management Tags: Brief Reports Source Type: research
Publication date: Available online 12 December 2018Source: Social Science &MedicineAuthor(s): Amelia M. Jamison, Sandra Crouse Quinn, Vicki S. FreimuthAbstractVaccine confidence depends on trust in vaccines as products and trust in the system that produces them. In the US, this system consists of a complex network connecting pharmaceutical companies, government agencies, and the healthcare system. We explore narratives from White and African American adults describing their trust in these institutions, with a focus on influenza vaccine. Our data were collected between 2012 and 2014 as part of a mixed-methods investigat...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
This article is protected by copyright. All rights reserved. PMID: 30548475 [PubMed - as supplied by publisher]
Source: European Journal of Immunology - Category: Allergy & Immunology Authors: Tags: Eur J Immunol Source Type: research
DeDiego Influenza A viruses (IAV) can infect a broad range of animal hosts, including humans. In humans, IAV causes seasonal annual epidemics and occasional pandemics, representing a serious public health and economic problem, which is most effectively prevented through vaccination. The defense mechanisms that the host innate immune system provides restrict IAV replication and infection. Consequently, to successfully replicate in interferon (IFN)-competent systems, IAV has to counteract host antiviral activities, mainly the production of IFN and the activities of IFN-induced host proteins that inhibit virus replication...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
TUESDAY, Dec. 11, 2018 -- After extensive adjustment for confounders, influenza vaccination is associated with a reduced risk for all-cause and cardiovascular death among patients with heart failure, according to a study published online Dec. 10 in...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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