FDA Clears Smart Watch to Detect Seizures, Manage Epilepsy FDA Clears Smart Watch to Detect Seizures, Manage Epilepsy

The FDA has cleared the first smart watch for seizure tracking and epilepsy management. The device uses advanced machine learning to identify convulsive seizures and send an alert via text and phone message to caregivers.FDA Approvals
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Alert Source Type: news

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Publication date: November 2018Source: Epilepsy &Behavior, Volume 88Author(s): Su Woan Wo, Lai Choo Ong, Wah Yun Low, Pauline Siew Mei LaiAbstractBecause of the nature of epilepsy, and the unpredictability of seizure recurrence, epilepsy requires long-term treatment with medications. As a consequence, epilepsy has a negative pervasive impact in children with epilepsy (CWE), and their parents. Hence, our aim was to explore the needs and challenges of parents and their CWE. In-depth interviews (IDIs) were conducted with 15 families (12 mothers and 3 fathers) and 15 CWE (aged 8–18 years). Data were transcribed ver...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
ConclusionsNeurophysiological techniques, in combination with neuroimaging studies, may shed light on the pathophysiological mechanisms of CBD. A better understanding of the disease processes may help clinicians to make a more accurate and early diagnosis. TMS, SEP, LLR, and co-evaluation of EEG and EMG can aid the in differentiation between CBD and other parkinsonism syndromes.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
We report a case of repeated drug induced OGCs in a 38 year old patient with secondary progressive multiple sclerosis. He was referred to our center for treatment of “intractable” epilepsy manifesting as episodic eye and head deviations with apparent unresponsiveness. In the epilepsy monitoring unit, ten typical spells were captured without epileptiform electroencephalographic correlates, but we discovered chronic exposure to metoclopramide. A diagnosis of OGC was suspected and Metoclopramide was stopped. This robustly improved the frequency of his spells. In a setting of usage of antidopaminergic medications...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 13 October 2018Source: Journal of Molecular Graphics and ModellingAuthor(s): Guedmiller S. Oliveira, Ariana S. Moraes, Yanyun Liu, Eduardo F. Franca, Luiz C.G. Freitas, James M. Briggs, Fabio L. LeiteAbstractBiomolecular immobilization was investigated using computer simulations in order to interpret the results obtained from the atomic force microscope (AFM). The dissociation pathway of an anti-epileptic drug called phenobarbital from an anti-phenobarbital antibody was studied for immunosensor purposes. Results shown that six favorable antibody configurations over the surface were found,...
Source: Journal of Molecular Graphics and Modelling - Category: Molecular Biology Source Type: research
Functional neurosurgery involves the surgical management of a wide range of neurological diseases with the aim of treating conditions such as movement disorders, spasticity, epilepsy and intractable pain. Functional neurosurgery began with ablative surgical techniques involving destruction of neural structures responsible for the aberrant neural pathways/networks causing pathology. In more recent years there has been a move away from the creation of permanent destructive lesions towards modulation of the neural networks utilizing neuromodulation.
Source: Surgery (Medicine Publishing) - Category: Surgery Authors: Tags: Neurosurgery Source Type: research
Epilepsy is one of the most common neurologic disorders, and often remains refractory despite pharmacologic treatment. In patients unamenable to surgical resection of seizure foci, vagal nerve stimulation (VNS) may provide benefit. Multiple case series have attempted to construct a risk profile for VNS, yet are largely confined to pediatric or single-center populations.
Source: World Neurosurgery - Category: Neurosurgery Authors: Tags: Original article Source Type: research
AbstractLanguage is mediated by pathways connecting distant brain regions that have diverse functional roles. For word production, the network includes a ventral pathway, connecting temporal and inferior frontal regions, and a dorsal pathway, connecting parietal and frontal regions. Despite the importance of word production for scientific and clinical purposes, the functional connectivity underlying this task has received relatively limited attention, and mostly from techniques limited in either spatial or temporal resolution. Here, we exploited data obtained from depth intra-cerebral electrodes stereotactically implanted ...
Source: Journal of Computational Neuroscience - Category: Neuroscience Source Type: research
AbstractPurpose of reviewDravet syndrome is a rare but severe genetic epilepsy that has unique treatment challenges. This is a review of current and future potential treatment options.Recent findingsTreatment for Dravet syndrome should encompass many aspects of the syndrome such as gait, behavior, and nutrition, as well as focus on seizure control. Many sodium channel blockers should be avoided as they are likely to exacerbate seizures. Current options for treatment include valproic acid, clobazam, stiripentol, and ketogenic diet. Testing is underway for several new treatment options with unique mechanisms of action and th...
Source: Current Treatment Options in Neurology - Category: Neurology Source Type: research
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Source: British Journal of Neurosurgery - Category: Neurosurgery Authors: Source Type: research
Clinical Case Reports, EarlyView.
Source: Clinical Case Reports - Category: General Medicine Authors: Source Type: research
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