Staphylococcus aureus dry-surface biofilms are more resistant to heat treatment than traditional hydrated biofilms

Conclusion S. aureus dry-surface biofilms are less susceptible to killing by dry heat and steam autoclaving than hydrated biofilms, which are less susceptible to heat treatment than planktonic suspensions.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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Publication date: Available online 18 November 2019Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Frantiescoli Anversa Dimer, Cristiane de Souza Carvalho-Wodarz, Adriely Goes, Katarina Cirnski, Jennifer Herrmann, Viktoria Schmitt, Linda Pätzold, Nadia Abed, Chiara De Rossi, Markus Bischoff, Patrick Couvreur, Rolf Müller, Claus-Michael LehrAbstractDrug delivery systems are promising for targeting antibiotics directly to infected tissues. To reach intracellular Staphylococcus aureus and Mycobacterium abscessus, we encapsulated clarithromycin in PLGA nanocapsules, suitable for aerosol delivery ...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
The original article [1] contains an error in Fig.  1 whereby sub-figures 1B, 1C&1D contain the wrong scale on the x-axis. The correct sub-figures are located ahead in this Correction article and should be considered instead.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
ConclusionsIn a model of osteomyelitis induced by MRSA, despite the failure in demonstrating antibacterial effectiveness of NBD peptide in vivo, the results suggest antibiotics in conjunction with NBD peptide to possibly have promising therapeutic potential in osteomyelitis.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Conclusion. The hexane extract of L. apiculata leaves showed the lower MIC against S. aureus when compared with extracts obtained from other parts of the plant. The growth curve and the colonies count suggest a bacteriostatic activity of the L. apiculata leaves extract against Staphylococcus aureus. PMID: 31737073 [PubMed]
Source: International Journal of Microbiology - Category: Microbiology Tags: Int J Microbiol Source Type: research
Publication date: Available online 18 November 2019Source: Innovative Food Science &Emerging TechnologiesAuthor(s): Oscar G. Martínez-Moreno, Luis M. Anaya-Esparza, Jorge A. Sánchez-Burgos, Libier Meza-Espinoza, Alejandro Pérez-Larios, J. Emanuel Bojorquez-Quintal, Efigenia Montalvo-GonzálezAbstractThe combined effect of vacuum, heat and ultrasound (vacuum-thermosonication, VTS) on soursop puree was investigated with regard to the viability of Escherichia coli and Staphylococcus aureus, inactivation of polyphenol oxidase and sensory quality. The VTS conditions were: vacuum (8.46, 11 and 16.9...
Source: Innovative Food Science and Emerging Technologies - Category: Food Science Source Type: research
The association between Salmonella spp. and osteoarticular infections in pediatric patients with major sickle hemoglobinopathies has been well established. However, the contemporary microbiology of these infections in such patients is unknown. We conducted a retrospective review of medical records at Texas Children’s Hospital in Houston from 2000 to 2018 to investigate this question. Fifty cases were identified. In 23 (46%) cases, a pathogen was identified. Salmonella was the most common pathogen isolated, accounting for 61% of culture-positive cases followed by Staphylococcus aureus (21.7%).
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Brief Reports Source Type: research
During my nine years in the NFL, I ruptured tendons in my fingers, suffered multiple concussions, and broke several bones. I tore my ACL, MCL, and PCL, and completely blew out my left knee. That last injury should have ended my career. But it didn’t. I put myself back together and played through the pain. What finally took me down? A tiny bug I had never heard of and couldn’t see. A drug-resistant staph infection called methicillin-resistant Staphylococcus aureus cost me my NFL career—and almost my life. MRSA is one of many deadly, antibiotic-resistant infections. Together, these “superbugs” k...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized health Source Type: news
Abstract During the course of screening for new metabolites from basidiomycetes, we isolated and characterized five previously undescribed secondary metabolites, skeletocutins M–Q (1–5), along with the known metabolite tyromycin A (6) from the fruiting bodies of the polypore Skeletocutis sp. The new compounds did not exhibit any antimicrobial, cytotoxic, or nematicidal activities. However, compound 3 moderately inhibited the biofilm formation of Staphylococcus aureus (S. aureus), while compounds 3 and 4 performed moderately in the ʟ-leucine-7-amido-4-methylcoumarin (ʟ-Leu-AMC) inhibition assay. These compound...
Source: Beilstein Journal of Organic Chemistry - Category: Chemistry Authors: Tags: basidiomycete polyporaceae secondary metabolites structure elucidation Full Research Paper Source Type: research
In this study, the obtained IC50 concentration of 51.25 μg/mL exhibits significant anticancer activity against A549 cells than other tested concentrations because of the release of zinc ions, which induce the cell apoptosis. Furthermore, studies on cell cycle validate that ZnO NPs arrest the cell cycle at the sub-G1 phase of A549 cells. These results suggest the utility of phytogenic ZnO NPs for various biomedical applications.Graphical abstract
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
The aim of this study was to determine the antimicrobial efficiency of piperitenone epoxide (PEO) – a principal component of various aromatic plants’ essential oil – in combination with various antibiotics against 28 strains of Staphylococcus aureus and 10 strains of Escherichia coli isolated from clinical samples. Mentha spicata’s essential oil, initially collected by hydrodistillation, was then subjected to flush column chromatography affording PEO of high purity. Minimum inhibitory concentrations of PEO alone and in combination with various concentrations of antibiotics were assessed using the mi...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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