‘VIOLET’ – a fluorescence-based simulation exercise for training healthcare workers in the use of personal protective equipment

Conclusion Simulation exercises using VIOLET provide evidence-based assessment of PPE ensembles, and are a valuable resource for training of healthcare staff in wearing and safe doffing of PPE.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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Publication date: Available online 14 November 2019Source: The Lancet Global HealthAuthor(s): Karoun H Bagamian, John D Anderson, Farzana Muhib, Oliver Cumming, Lindsey A Laytner, Thomas F Wierzba, Richard RheingansSummaryBackgroundDiarrhoea, a global cause of child mortality and morbidity, is linked to adverse consequences including childhood stunting and death from other diseases. Few studies explore how diarrhoeal mortality varies subnationally, especially by cause, which is important for targeting investments. Even fewer examine indirect effects of diarrhoeal morbidity on child mortality. We estimated the subnational d...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Lancet Countdown tracks impacts of global heating covering disease, wildfires and malnutritionThe climate crisis will determine the lifelong health of today ’s children, doctors have warned, noting that global heating was already causing harm.Children are especially vulnerable and the global team of researchers say rising temperatures mean the bacteria causing deadly diarrhoea will thrive while poorer crop yields could lead to more malnutrition.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Climate change Global health Infectious diseases Malnutrition Wildfires Natural disasters and extreme weather Children Global development Environment World news UK news Science Agriculture Source Type: news
Publication date: Available online 11 November 2019Source: The LancetAuthor(s): Stephen A Harrison, Mustafa R Bashir, Cynthia D Guy, Rong Zhou, Cynthia A Moylan, Juan P Frias, Naim Alkhouri, Meena B Bansal, Seth Baum, Brent A Neuschwander-Tetri, Rebecca Taub, Sam E MoussaSummaryBackgroundNon-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis, inflammation, hepatocellular injury, and progressive liver fibrosis. Resmetirom (MGL-3196) is a liver-directed, orally active, selective thyroid hormone receptor-β agonist designed to improve NASH by increasing hepatic fat metabolism and reducing lipotoxicity....
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 11 November 2019Source: Preventive Veterinary MedicineAuthor(s): V. Fruscalso, G. Olmos, M.J. HötzelAbstractOur retrospective, cross-sectional study aimed to identify the mortality rate of preweaned heifer calves and associated herd-management factors in family-run dairy holdings in the state of Rio Grande do Sul, Brazil. A survey was made available through an online platform to all the municipalities (n = 494) with a state official extension office (Emater), allowing for any milk producer in RS raising the calves on-farm to take part in the study. A total of 1,451 fram...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
We examined 252 rectal swabs obtained from 134 roe deer (Capreolus capreolus), 97 red deer (Cervus elaphus) and 21 fallow deer (Dama dama) in north-eastern Poland. The samples were enriched in modified buffered peptone water. Polymerase chain reaction (PCR) assays were conducted to determine the virulence profile of stx1, stx2 and eae or aggR genes, to identify the subtypes of stx1 and stx2 genes, and to perform O and H serotyping. E. coli O157:H7 isolates were detected in the rectal swabs collected from 1/134 roe deer (0.75%) and 4/97 red deer (4.1%), and they were not detected in fallow deer (Dama dama). The remaining E....
Source: Food Microbiology - Category: Food Science Authors: Tags: Food Microbiol Source Type: research
In this study a clinically meaningful prolongation of PFS by 2.2 months was observed. In addition, the time to intervention for brain metastases was prolonged in the neratinib group and the cumulative incidence of brain metastases was lower as well. On the downside a high rate of grade 2 and  3 diarrhoea was observed.
Source: Memo - Magazine of European Medical Oncology - Category: Cancer & Oncology Source Type: research
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Source: Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Spinal Cord, Published online: 11 November 2019; doi:10.1038/s41393-019-0369-yStudy protocol of a double-blind randomised placebo-controlled trial on the effect of a multispecies probiotic on the incidence of antibiotic-associated diarrhoea in persons with spinal cord injury
Source: Spinal Cord - Category: Research Authors: Source Type: research
ConclusionThe countries in this region needs to work hard to reduce this burden. This requires huge investment especially the finance and human resource development.
Source: International Journal of Africa Nursing Sciences - Category: African Health Source Type: research
Publication date: December 2019Source: The Lancet Global Health, Volume 7, Issue 12Author(s): Geetha R Menon, Lucky Singh, Palak Sharma, Priyanka Yadav, Shweta Sharma, Shrikant Kalaskar, Harpreet Singh, Srividya Adinarayanan, Vasna Joshua, Vaitheeswaran Kulothungan, Jeetendra Yadav, Leah K Watson, Shaza A Fadel, Wilson Suraweera, M Vishnu Vardhana Rao, R S Dhaliwal, Rehana Begum, Prabha Sati, Dean T Jamison, Prabhat JhaSummaryBackgroundMany countries, including India, seek locally constructed disease burden estimates comprising mortality and loss of health to aid priority setting for the prevention and treatment of disease...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
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