circRNA_0046366 inhibits hepatocellular steatosis by normalization of PPAR signaling.

CONCLUSION: Dysregulation of circRNA_0046366/miR-34a/PPARα signaling may be a novel epigenetic mechanism underlying hepatocellular steatosis. circRNA_0046366 serves as a potential target for the treatment of hepatic steatosis.
PMID: 29391755 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - January 21, 2018 Category: Gastroenterology Authors: Guo XY, Sun F, Chen JN, Wang YQ, Pan Q, Fan JG Tags: World J Gastroenterol Source Type: research