Flu in U.S. now widespread but season may be peaking: CDC

CHICAGO (Reuters) - Seasonal influenza is now widespread across the continental United States, causing severe illness and rising numbers of hospitalizations, but this year's outbreak may be peaking, government health officials said on Friday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Source: Transboundary and Emerging Diseases - Category: Veterinary Research Authors: Tags: Original Article Source Type: research
Authors: Mandil A, Bresee J, Tageldin MA, Azad TM, Khan W Abstract Infectious diseases continue to represent a significant threat to global health security, particularly in the context of increasing globalization, interconnectedness and interdependence. Chief among such threats are influenza viruses and other respiratory pathogens, such as Middle East Respiratory Syndrome coronavirus (MERS-CoV), because of their risk of high transmissibility and acuity of illness. Annual epidemics of seasonal influenza cause an estimated 3-5 million cases of severe illness and more than 500 000 deaths, with the prospect of pandemic...
Source: Eastern Mediterranean Health Journal - Category: Middle East Health Tags: East Mediterr Health J Source Type: research
(Columbia University's Mailman School of Public Health) Most of us are aware of the seasonal cycle of influenza outbreaks, which for Americans peak in the winter. In a new paper, Micaela Martinez, Ph.D., a scientist at the Columbia Mailman School of Public Health, makes a case that all infectious diseases have a seasonal element. The 'Pearl' article appears in the journal PLOS Pathogens.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Publication date: Available online 2 November 2018Source: Veterinary MicrobiologyAuthor(s): Celia Abolnik, Savannah Stutchbury, Marthinus Jacobus HartmanAbstractReported mass mortalities in wild pigeons and doves during the 2017/2018 Clade HPAI H5N8 outbreaks in South Africa necessitated an investigation of healthy racing pigeons for their susceptibility and ability to transmit a Clade sub-group B virus of South African origin. Pigeons challenged with medium (104.5 EID50) and high doses (106 EID50) but not a low dose (103 EID50) of virus, shed virus in low levels of
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Abstract From 2005 to July 6, 2018, a total of 435 swine-origin influenza A H3N2 variant virus (H3N2v) human infections were reported in the USA. The largest H3N2v outbreak in the USA occurred in 2011-2012. This virus obtained the HA gene from human seasonal H3N2 influenza A viruses (seasonal H3N2) via human-to-swine transmission in the mid-1990s and was classified as Cluster IV H3N2v. For early detection of public health threats associated with Cluster IV H3N2v in distinction from seasonal H3N2, we developed highly specific and sensitive one-step real-time RT-PCR assays directly targeting the HA genes of Cluster ...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research
CONCLUSION: Common themes have emerged from the Canadian literature addressing barriers and facilitators of vaccination during pregnancy. However, there is a paucity of literature to suggest strategies to improve the uptake of vaccination during pregnancy in Canadian settings. Further research is urgently needed given the expanding role of vaccination during routine prenatal care. PMID: 30361161 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Abstract On September 17, 2017, the Maryland Department of Agriculture (MDA) was notified by fair and 4-H officials of ill swine at agricultural fair A, held September 14-17. That day, investigation of the 107 swine at fair A revealed five swine with fever and signs of upper respiratory tract illness. All five respiratory specimens collected from these swine tested positive for influenza A virus at the MDA Animal Health Laboratory, and influenza A(H3N2) virus was confirmed in all specimens by the U.S. Department of Agriculture National Veterinary Services Laboratory (NVSL). On September 18, MDA was notified by fai...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
The Food and Drug Administration (FDA) has approved a new antiviral influenza treatment. The agency on Wednesday approved Genentech’s drug Xofluza, which can be taken via a single oral dose to help patients recover more quickly from the flu. It’s the “first new antiviral flu treatment with a novel mechanism of action approved by the FDA in nearly 20 years,” FDA Commissioner Dr. Scott Gottlieb said in a statement. The main factor differentiating Xofluza from other antiviral flu treatments on the market, such as Tamiflu and Relenza, is the way it’s taken. Xofluza is the only antiviral that can b...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs healthytime onetime Source Type: news
Publication date: Available online 23 October 2018Source: EpidemicsAuthor(s): Martha I. Nelson, James O. Lloyd-Smith, Lone Simonsen, Andrew Rambaut, Edward C. Holmes, Gerardo Chowell, Mark A. Miller, David J. Spiro, Bryan Grenfell, Cécile ViboudAbstractDue to a combination of ecological, political, and demographic factors, the emergence of novel pathogens has been increasingly observed in animals and humans in recent decades. Enhancing global capacity to study and interpret infectious disease surveillance data, and to develop data-driven computational models to guide policy, represents one of the most cost-effective...
Source: Epidemics - Category: Epidemiology Source Type: research
Abstract The seasonal outbreaks of influenza infection cause globally respiratory illness, or even death in all age groups. Given early-warning signals preceding the influenza outbreak, timely intervention such as vaccination and isolation management effectively decrease the morbidity. However, it is usually a difficult task to achieve the real-time prediction of influenza outbreak due to its complexity intertwining both biological systems and social systems. By exploring rich dynamical and high-dimensional information, our dynamic network marker/biomarker (DNM/DNB) method opens a new way to identify the tipping p...
Source: J Cell Mol Med - Category: Molecular Biology Authors: Tags: J Cell Mol Med Source Type: research
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