Spike in flu cases as fears grow over NHS winter pressure
GP consultations for flu-like symptoms rose in all UK countries in the final week of 2017, while hospital admissions for influenza soared to 'very high' levels, as signs grew that flu could put the NHS under growing pressure this winter.
Susan L. Baldwin, Fan-Chi Hsu, Neal Van Hoeven, Emily Gage, Brian Granger, Jeffrey A. Guderian, Sasha E. Larsen, Erica C. Lorenzo, Laura Haynes, Steven G. Reed, Rhea N. Coler
World Health Organization. 05/30/2017 This course introduces the concept of pandemic influenza severity assessment and covers its required steps, from choosing data to using, reporting, and communicating severity estimates. It describes why assessing influenza severity is important; when and how to assess influenza severity; how to communicate severity assessment findings; and how to contribute to a global influenza severity assessment. (Video or Multimedia) Site requires free registration.
Condition: Influenza Interventions: Biological: Immunose™ FLU 1%; Biological: Immunose™ FLU 2%, 200 μl; Biological: Immunose™ FLU 2%, 300 μl; Biological: Influenza antigen; Drug: Placebo; Biological: i.m comparator Sponsor: Eurocine Vaccines AB Recruiting
Conditions: Influenza, Human; Pregnancy; Birth Defect Interventions: Biological: Flucelvax Trivalent Influenza Vaccine; Biological: Flucelvax Quadrivalent Influenza Vaccine Sponsor: Seqirus Recruiting
Publication date: Available online 18 February 2018 Source:Journal of Molecular Biology Author(s): Aneth S. Canale, Sergey V. Venev, Troy W. Whitfield, Daniel R. Caffrey, Wayne A. Marasco, Celia A. Schiffer, Timothy F. Kowalik, Jeffrey D. Jensen, Robert W. Finberg, Konstantin B. Zeldovich, Jennifer P. Wang, Daniel N.A. Bolon The fitness effects of synonymous mutations can provide insights into biological and evolutionary mechanisms. We analyzed the experimental fitness effects of all single nucleotide mutations, including synonymous substitutions, at the beginning of the influenza A virus hemagglutinin (HA) gene. Many syn...
BackgroundThe aim of this study was to estimate excess pneumonia and influenza (P&I) hospitalizations during influenza epidemics and measure their correlation with influenza vaccine coverage in the 65 and more years old, according to the type/subtype of influenza virus. MethodsThe study period comprised week 40/1998‐40/2015. Age‐specific weekly P&I hospitalizations (ICD‐9: 480‐487) as main diagnosis were extracted from the National Hospital Discharge database. Age‐specific baseline hospitalization rates were estimated by autoregressive integrated moving average (ARIMA) model without time periods with excess hospi...
In this study, we report risk factors for mortality, invasive ventilation and use of vasoactive drugs for children admitted to PICU with influenza.