Everybody In! No Bouncers at Tumor Gates.

Everybody In! No Bouncers at Tumor Gates. Trends Genet. 2017 Dec 22;: Authors: Vitale I, Galluzzi L Abstract Two recent genomic studies suggest that a large fraction of human tumors evolves in the presence of limited negative selection against somatic mutations. In this context, specific genetic defects enable the establishment of a hypermutant state that may constitute a target for immunotherapeutic interventions. PMID: 29277455 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29277455?dopt=Abstract

Source: Trends in Genetics : TIG - December 22, 2017 Category: Genetics & Stem Cells Authors: Vitale I, Galluzzi L Tags: Trends Genet Source Type: research

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