Activin A, B and AB increase human trophoblast cell invasion by up-regulating N-cadherin.

Conclusion: Activin A, B and AB produce comparable increases in human trophoblast cell invasion by up-regulating N-cadherin expression in a SMAD2/3-SMAD4-dependent manner.
PMID: 25105734 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - August 8, 2014 Category: Endocrinology Authors: Li Y, Klausen C, Cheng JC, Zhu H, Leung PC Tags: J Clin Endocrinol Metab Source Type: research