Donor-Lung Preservation Device Approved

Technology may lead to more transplants, FDA says
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Authors: Tags: Pharmacy, Pulmonology, FDA Approvals, Source Type: news

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Specialized T cells in induced bronchus-associated lymphoid tissue regulate alloimmune responses in the lung allograft.
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Editors ' Choice Source Type: research
We read with great interest the review by Yanagawa et al, entitled Surgery for tumors of the heart,1 where the authors thoroughly review cardiac tumors classification, diagnosis sequence as well as the suggested method of treatment for the different kinds of tumors. The authors address sarcoma's as one of the rare malignant tumors and suggest a two-step surgical approach to sarcoma that involve the heart and lung.
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ADULT – Letter to the Editor Source Type: research
Zerina Nelson, four, of Mesa, Arizona, was diagnosed with Hermansky-Pudlak syndrome, a genetic condition characterized by albinism and vision considered legally blind
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conditions:   Lung Transplant Rejection;   Antibody-mediated Rejection Interventions:   Drug: Belatacept;   Drug: Carfilzomib Sponsors:   Duke University;   Bristol-Myers Squibb Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We present a case of endobronchial fusariosis following bilateral sequential lung transplantation for idiopathic pulmonary arterial hypertension in a 13 years old boy who was treated successfully with posaconazole and nebulized amphotericin B. We discuss the role of nebulized amphotericin B in treating invasive pulmonary fungal disease in children. To our knowledge, this is the first pediatric case of endobronchial fusariosis reported in the literature.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research
Chronic lung allograft dysfunction or CLAD, encompasses a variety of phenotypes including both obstructive and restrictive phenotypes as detected by pulmonary function testing (PFTs), and has advanced the understanding of current clinical guidelines1-5. From the initial classification of chronic lung allograft rejection based primarily on pulmonary function testing, clinical guidelines now encompass CLAD phenotypes, presumed causes, characteristic imaging findings, and refinement of histopathological grades.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
Abstract Ceftolozane-tazobactam (C/T) pharmacokinetics during extracorporeal membrane oxygenation (ECMO) has not been previously studied. In this work we report on the C/T plasmatic levels in a lung transplant (LTX) recipient during ECMO, treated with C/T (i.v., 2 g ceftolozane and 1 g tazobactam, every 8 hours]) for a Pseudomonas aeruginosa pulmonary infection. PMID: 30642936 [PubMed - as supplied by publisher]
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
"For your eyes only": ophthalmic complications following lung transplantation. J Thorac Dis. 2018 Nov;10(11):6285-6297 Authors: Dhal U, Raju S, Singh AD, Mehta AC Abstract Ophthalmic complications in the lung transplant population are a little-known entity. It includes a spectrum of diseases ranging from infections such as cytomegalovirus (CMV) retinitis, herpetic keratitis, Pseudallescheria boydii to non-infectious complications such as posterior subcapsular cataracts (PSCs), cyclosporine retinopathy, and post-transplant lymphoproliferative disorder (PTLD). These diseases can be attributed t...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Authors: Poggi C, Mantovani S, Pecoraro Y, Carillo C, Bassi M, D'Andrilli A, Anile M, Rendina EA, Venuta F, Diso D Abstract Chronic obstructive pulmonary disease (COPD) is the major causes of disability and mortality. The efficacy of maximal medical treatment, although effective at the early stages of the disease, becomes limited when extensive alveolar destruction is the main cause of respiratory failure. At this stage of the disease more aggressive options, when feasible, should be considered. Lung transplantation and lung volume reduction surgery (LVRS) are currently available for a selected group of patients. E...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
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