HIV Drug Raltegravir Approved for Neonates HIV Drug Raltegravir Approved for Neonates

Raltegravir is the only integrase inhibitor approved in the US for treatment of HIV in newborns from birth to 4 weeks of age weighing at least 2 kg.FDA Approvals
Source: Medscape Pharmacist Headlines - Category: Drugs & Pharmacology Tags: HIV/AIDS News Alert Source Type: news

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Conclusions: Although KS incidence rates have decreased nationally, age, racial, and geographic disparities persist, including increasing risk among younger Black men and particularly elevated rates in some southern states and urban areas. Further research is needed to address racial and geographic AIDS-related KS disparities.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Epidemiology Source Type: research
Background: Falls and fall risk factors are common among people living with HIV (PLWH). We sought to identify fall risk factors among men with and without HIV. Methods: Men aged 50–75 years with (n = 279) and without HIV (n = 379) from the Bone Strength Substudy of the Multicenter AIDS Cohort Study were included. Multinomial logistic regression models identified risk factors associated with falling. Results: One hundred fourteen (41%) PLWH and 149 (39%) of uninfected men had ≥1 fall; 54 (20%) PLWH and 66 (17%) of uninfected men experienced ≥2 falls over 2 years. Five and 3% of PLWH and uninfected men, r...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Clinical Science Source Type: research
Most survey respondents believe burnout is tied to lower quality of care
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news
HIV-positive patients who need a new kidney have delayed referral to transplant programs and spend more time on the waitlist, according to preliminary data from two independent studies presented June 4 at the American Transplant Congress in Boston.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news
[Foroyaa] HIV prevalence among women aged between 20 to 29 years, is reported to be higher than among men of the same age in Western and Central African countries.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
Background: The global mortality from HIV and the cutaneous burden of infective, inflammatory and malignant diseases in the setting of AIDS have significantly declined following the advent of highly active antiretroviral therapy. Regrettably, there has been a contemporaneous escalation in the incidence of adverse cutaneous drug reactions (ACDR), with studies attesting that HIV-positive individuals are a hundred times more susceptible to drug reactions than the general population, and advanced immunodeficiency portending an even greater risk. Several variables are accountable for this amplified risk in HIV.Summary: Adverse ...
Source: Dermatopathology - Category: Pathology Source Type: research
In 2013, a novel thermally dimorphic fungal pathogen was described to cause disseminated disease among persons living with advanced HIV/AIDS in South Africa. Although the organism was initially described as anEmmonsia-like fungus, it is now known to belong to a new genus of thermally dimorphic fungi and was recently namedEmergomyces africanus. There is considerable clinical and histopathological overlap between emergomycosis and histoplasmosis. This review addresses taxonomic, clinical, diagnostic, and therapeutic aspects ofEs. africanus disease, a condition which has, to date, only been reported from southern Africa.Derma...
Source: Dermatopathology - Category: Pathology Source Type: research
Source: AIDS Care - Category: Infectious Diseases Authors: Source Type: research
Source: AIDS Care - Category: Infectious Diseases Authors: Source Type: research
In this study, we reconstruct the dynamics of dissemination of early divergent non-pandemic subtype B lineages (designated BCAR) in Hispaniola. To this end, we analyzed 127 HIV-1 subtype B pol sequences collected in Haiti between 2009 and 2014, combined with BCAR pol sequences from Haiti (n = 12) and the Dominican Republic (n = 123) previously described. Phylogenetic analyses supported that BCAR strains account for most (>70%) of HIV-1 subtype B infections in Haiti. The BCAR strains from Haiti and the Dominican Republic were highly intermixed among each other, although the null hypothesis of completely random mixing was...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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