Microbiota and Aging. A Review and Commentary

Although there is a consensus that the dominant species that make up the adult microbiota remains unchanged in elderly people, it has been reported that there are significant alterations in the proportion and composition of the different taxa, leading to reduced microbiota diversity, as well as an increase of enteropathogens that may lead to chronic inflammation. The ageing of mucosal immune and motor systems also contributes to these changes. As the individual ages, there is a loss in the number of Peyer's patches, an altered local capacity of T and B cell functions as well as chronic macrophage activation.

Source: Archives of Medical Research - December 8, 2017 Category: Research Authors: Carmen Garc ía-Peña, Teresa Álvarez-Cisneros, Ricardo Quiroz-Baez, Robert P. Friedland Tags: Review Article Source Type: research