Inhibin-A and inhibin-B in cyclic and pregnant mares, and mares with granulosa-theca cell tumors: Physiological and diagnostic implications

Studies in mares have examined serum inhibin concentrations using immuno-assays unable to distinguish dimeric inhibin-A from inhibin-B isoforms. Inhibin-A and inhibin-B immuno-assays were used to investigate concentrations in cyclic mares, young and old (6 vs 19 years old, respectively) mares following hemi-ovariectomy, mares during pregnancy and in mares with confirmed granulosa cell tumors (GCTs). Mares with inter-ovulatory intervals of 26 days had ovulatory peaks of inhibin-A averaging 80  pg/mL with a mid-cycle nadir of 5 pg/mL.

Source: Theriogenology - December 7, 2017 Category: Genetics & Stem Cells Authors: A.J. Conley, E.L. Scholtz, G. Dujovne, R.F. Cotterman, E.L. Legacki, R.C. Uliani, M.A. Alvarenga, B.A. Ball, B. Kalra, G.V. Savjani, A. Kumar Source Type: research